Central Nervous System drugs Flashcards

1
Q

Define nueropharmacology.

A

Study of drugs that after processes controlled by the nervous system

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2
Q

What is CNS drugs?

A

Used by psychiatric disorders, suspression of seizures, relief of pain, production of anesthesia

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3
Q

What does metabolosism mean?

A

Change medications into less active/ inactive form by the action of enzymes

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4
Q

What does axonal conductation do?

A

Conducting an action potential down the axon of the neuron

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5
Q

What does synaptic transmission do?

A

Process by which imformation is carried a cross the gap between nueron and postsynaptic cell

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6
Q

Bloodbrain barrier do?

A

Impedes the entry of drug into the body

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7
Q

What is parkinson’s disease?

A

Slowly progressive nuerodegenerative disorder characterized by tremor, rigidity, postural instability and slowed movement

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8
Q

What is assesment?

A

Assess motor symptoms and the extent which they interfere which acitivites of daily living

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9
Q

What is therapeutic goal?

A

Improve the patient’s ability to carry out activities of daily life

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10
Q

Dopaminergic drugs do?

A

Direclty/indirectly cause activation of dopamine receptors

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11
Q

Anticholinergic agents do?

A

Drugs that block receptors for ACh

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12
Q

What is epilepsy?

A

Group of disorders characterized by excessive exitablility of nuerons of the CNS

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13
Q

Seizure means?

A

General term that appllies to all of epileptic events

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14
Q

Convulsion means?

A

Abnormal motor phenomenon

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15
Q

What is partial seizures?

A

Excitation undergoes limited spread from the focus to adjacent cortical areas

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16
Q

What is generalized seizures?

A

Excitation spreads widely throughout both hemispheres of the brain

17
Q

What is phenytoin?

A

Most commonly prescribed anticonvulsant drug

18
Q

What is phenobarbital?

A

Effective againts partial seizures and generalized tonic-clonic seizures but not absence seizures

19
Q

What is carbamazepine?

A

Cornerstone of epilepsy therapy and active againt partial seizures and tonic-clonic seizures but not absence seizures

20
Q

What is nueromuscular blocking drugs?

A

Relax skeletal muscle by disrupting the transmission of nerve impulse at the motor and plate