Central nervous system Flashcards
When is asymmetry of motor skills (i.e. hand dominance) abnormal?
<1 year
What system classifies motor functional ability? e.g. in CP, and what are the levels?
Gross Motor Function Classification System (GMFCS)
1: walks without limitations
2: walks with limitations
3: walks using a handheld mobility device
4: self-mobility with limitations; may use powered mobility
5: transported in a manual wheelchair
Types of CP
- Spastic
- unilateral (hemiplegia)
- bilateral (quadriplegia)
- bilateral (diplegia) - Dyskinetic
- Ataxic (hypotonic)
Features of spasticity in CP
- velocity-dependent: the faster it’s stretched the greater the resistance
- hallmark of spasticity: ‘dynamic catch’
- clasp knife (increase tone may suddenly yield under pressure)
What is unilateral (hemiplegia) spastic CP and the cause?
- damage to UMN
- arm and leg on opposite side to lesion affected
What is bilateral (quadriplegia) spastic CP and the cause?
- damage to UMN
- all 4 limbs affected, often severely
What is bilateral (diplegia) spastic CP and the cause?
- damage to UMN
- all 4 limbs but legs much more affected than arms
What is dyskinetic CP and the cause?
- damage/dysfunction in basal ganglia or associated pathways (extrapyramidal)
- dyskinesia = involuntary, uncontrolled movements
- chorea - irregular, sudden, brief, dance-like movements (non-repetitive)
- athetosis - slow writhing movements distally
- dystonia - simultaneous contraction of agonist and antagonist muscles of trunk and proximal muscles, causing twisting appearance
What is ataxic (hypotonic) CP and the cause?
- mostly genetic
- if acquired: cerebellum or its connections
- signs on same side as lesion
- early trunk and limb hypotonia, poor balance, delayed motor movements
- later incoordinate movements, intention tremor, ataxic gait
What medications are used to relax muscles in CP?
- diazepam
- baclofen (can be given intrathecally)
- botulinum injections
Features of febrile convulsions (consider another diagnosis if these are not present)
- generalised tonic clonic
- <15mins
- without recurrence within next 24h or within same febrile illness
Age range for febrile seizures
6 months - 6 years
What features suggest a focal frontal seizure?
motor phenomena
What features suggest a focal temporal seizure?
auditory or sensory (smell or taste) phenomena
What features suggest a focal occipital seizure?
positive or negative visual phenomena