Central Nervous System Flashcards
What protects the brain? (4)
- bony structures
- membranes
- BBB
- CSF
Meninges
= thin membranes located between bone and nervous tissue 3 layers: dura arachnoid pia
Dura mater has 2 layers…
- periosteal (external)
2. meningeal (internal)
There are 3 extensions of the dura mater which separate parts of the brain…
- falx cerebri: separates hemispheres of cerebrum
- falx cerebelli: separates hemispheres of cerebellum
- tentorium cerebelli: separates cerebrum from cerebellum
BBB
- how does it protect the brain?
= blood brain barrier
» isolates the parenchymal of the brain
» prevents many things from crossing into the brain and disturbing function
Arteries to brain
Internal carotid and vertebral arteries
Veins from brain
internal jugular veins
How much of oxygen does the brain consume?
20% of O2 and glucose
What are the tight junctions in the BBB formed from?
the vascular endothelium around brain capillaries
What do astrocytes do in the BBB?
Pressup against the capillaries and secrete chemicals which maintain the permeability of the tight junctions!
CSF
- how does it protect the brain?
= clear fluid; contains mostly water
- protects brain from physical and chemical injury
- transports nutrients and waste between blood and nervous tissues
How does the CSF circulate?
through internal cavities in the brain»_space; the ventricles
flows over and around the brain and sc in the subarachnoid space
What are functions of the CSF? (3)
- mechanical protection
- homeostasis
- Circulation
mechanical protection
- shock absorbing
- floats the brain
homeostasis
- pH of CSF effects pulmonary ventilation and cerebral blood flow > it is IMPORTANT To maintain homeostatic controls for brain tissue use
- also there is a transport system for hormones
circulation
-exchange of nutrients/waste between blood and adjacent nervous tissue
How is CSF produced?
is manufactured by the:
choroid plexus = blood capillaries and ependymal cells in ventricles walls
Where does the brainstem lie?
Between the diencephalon and sc
What is the medulla oblongata? where does it lie?
most inferior section of brain stem. Is involved in the regulation of essential functions for basis survival - breathing -cardiovascular (BP, HR) - swallowing, coughing, vomiting
What are the pons? where do they lie?
connection bridge between medulla and midbrain; anterior to cerebellum
contains breathing centres
-pnuemotaxic
-apneustic
What is the midbrain? where does it lie?
extends from pons to diencephalon
- where the cerebral aqueduct passes through (connects ventricles 3 and 4)
- visual reflexes > blinking
- auditory reflexes > startle
What is the reticular formation? Where is it?
small clusters of neuronal cell bodies interspersed with myleinated axons
- extend from sc throughout brain stem until diencephalon
- has ascending and descending tracts…
What is the reticular activating system (RAS)
sensory axons projecting from RF through cerebral cortex
-sensory stimuli include:
> visual and auditory
> pain, touch, pressure
The Ras…
- mediates consciousness
- sleep and arousal
- prevents damage > prolonged coma
- prevents sensory overload “filter”
What is the cerebellum? Where does it lie?
the little brain
second largest part of the brain
inferior to cerebrum, posterior to brain stem
separated from cerebrum by the transverse fissure