Central Dogma Flashcards
What is a continuous process in central dogma after the formation of DNA?
Replication
What are the steps of the Central Dogma?
DNA–>Replication—> Transcription—> RNA—> Translation=Protein
What are the three fundamental rules of replication?
It is semiconservative, semidiscontinuous, and bidirectional
What strand copies continuously?
the leading strand
What strand compies in segments?
the lagging strand and the must be joined
Where does Prokaryote DNA replication occur?
the cytoplasm
Where does Eukaryotic DNA replication occur?
nucleus
The leading strand is?
5’ to 3’
The lagging strand is?
3’ to 5’
What enzyme has a pocket with two regions?
DNA Polymerase
What are the two regions on DNA Polymerase?
Insertion and Post Insertion site
Where the incoming nucleotide binds is called?
the insertion site
What is the post-insertion site?
where the newly made base pair resides when the polymerase moves forward
What corrects any errors in the replication process?
The exonuclease
How mant DNA Polymerases are there?
five
What does DNA Polymerase 1 do?
its primary function is to clean up the replication process. (Its the most abundant)
What does DNA Polymerase 3 do?
It is the principal replication polymerase
What do DNA Polymerase 2,4, and 5 do?
They are involved in DNA repair
