Cellular structure and function (Chapter 3) Flashcards
what are organelles in eukaryotic cells?
Eukaryotic cells have folded membranes and intracellular compartments called organelles.
how can organelles help molecules?
This assists molecules to get to their desired destination.
what do each organelle do?
- is responsible for a specific ‘task’.
- allow different chemical reactions to occur at the same time in different places without interfering with each other
- maintain concentration of molecules at levels that ensure reactants will collide with each other at optimal rates
what is the role of the cell membrane?
- The boundary of a cell
- Determines cell identity
- Receives external signals
- Transports materials
where is cell wall vs cell membrane?
- Cell wall is found in plant cell and cell membrane is found in both plant and animal cells.
- Cell membrane is covered by the cell wall which forms the outermost covering of plant cells
- Cell wall is completely permeable whereas cell membrane is semi-permeable.
- Cell wall is made up of cellulose and cell membrane is made up of lipids (fats) and proteins.
what is the size of the cell/plasma membrane?
Plasma membranes range from 5 to 10 nm in thickness.
size comparison to plasma membrane?
For comparison, human red blood cells, visible via light microscopy, are approximately 8 µm wide, or approximately 1,000 times wider than a plasma membrane. Can only be seen with a electron microscope.
what do lipids include?
Fats and oils: important as energy-storing molecules
Phospholipids: important component of cell membranes
Steroids: hormones and vitamins
lipids characteristics?
- Contain little water & insoluble in water (hydrophobic)
- Form effective barrier between two watery environments
what is the cell membrane made of?
phospholipids
what are phospholipids made of?
- 2 hydrophobic fatty acid hydrocarbon tails
- Hydrophilic phosphate group attached to the glycerol & other small groups to the phosphate
what polarity is the phospholipid head?
hydrophilic polar head
what polarity is the phospholipid tail?
hydrophobic non polar tail
what is in the structure of the plasma membrane?
- transmembrane protein
- protein channel
- glycolipid
- cholesterol
- peripheral protein
- integral proteins
- carbohydrate hain
- phospholipid bilayer
- glycoprotein
what model is the plasma membrane?
‘The fluid mosaic model’
how is the plasma membrane a fluid mosaic model?
Comprises a phospholipid bilayer into which proteins & glycoproteins protrude
- Lipids are the ‘fluid’ part
- Proteins are the ‘mosaic’ part
- Membrane proteins have a variety of functions
Many proteins are glycoproteins
what do some proteins in the plasma membrane form?
Some proteins form channels to assist the movement of materials into & out of cell
what are the two types of proteins
- integral membrane proteins
- peripheral membrane proteins
what are integral membrane proteins?
Integral membrane proteins, also called intrinsic proteins, have one or more segments that are embedded in the phospholipid bilayer.
what are peripheral membrane proteins?
Peripheral membrane proteins, or extrinsic proteins, do not interact with the hydrophobic core of the phospholipid bilayer.
what is the importance of the plasma membrane?
- Cells membranes have proteins called receptors that bind to signaling molecules and initiate a physiological response.
- Recognising ‘self’ and ‘non-self’
- Crossing the membrane
why is the plasma membrane important for signalling?
Because membrane receptors interact with both extracellular signals and molecules within the cell, they can affect cell function without actually entering the cell.
how does the plasma membrane recognise self or non self?
- on outer surface are substances called antigens (glycoproteins – signal receivers)
- a person’s antigens are unique to that person i.e. like a fingerprint
- antigens perform an important role in the immune system
how permeable is the plasma membrane?
plasma membrane is semi-permeable or selectively permeable, therefore allowing only some dissolved materials to cross it
what does a selectively permeable cell membrane mean?
A selectively permeable cell membrane is one that allows certain molecules or ions to pass through it by means of active or passive transport.
what are factors governing substances crossing a membrane?
- Size
- Degree of polarity
- Not permeable to charged atoms (ions) and metallic ions
how does size affect permeability?
- Permeable to small molecules
- O2 (2 atoms), CO2 (3 atoms), ethanol (8 atoms), and H2O (3 atoms) due to its small size are permeable – but moves at a reduced rate
- Not permeable to larger hydrophilic polar molecules, e.g glucose (24 atoms)
how does degree of polarity affect permeability?
- Permeable to hydrophobic molecules
- May have receptors to help
what do charged atoms (ions) and metallic ions need to permeate the plasma membrane?
- Need channels
summary of how substances can permeate the plasma membrane?
- Lipid-soluble substances of various sizes, such as alcohol, are able to simply dissolve into the phospholipid bilayer and pass easily through membranes.
- Tiny molecules, such as water & urea, can pass between the phospholipid molecules.
- Small uncharged molecules, such as oxygen and carbon dioxide, can also pass through the phospholipid bilayer.
- Larger water-soluble substances, including amino acids and sugars, pass through channels made from protein molecules.