Cellular respiration Flashcards

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1
Q

What is cellular respiration and the purpose

A
  • Cellular respiration: the process by which food (glucose) is converted
    into useable energy (ATP)
  • Purpose: to produce energy in the form of ATP
  • The food/nutrients used for cellular respiration are the three major
    biomolecules found in living organisms
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2
Q

What is ATP

A

Adenosine triphosphate (ATP) is the energy currency/energy molecule
for cells. ATP molecules store energy using a very high energy phosphate bond. This bond can be broken to provide energy

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3
Q

ATP 🡪 ADP

A

After the energy is given away, ATP becomes ADP (adenosine
diphosphate) and can return to the mitochondria to be recycled

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4
Q

What is ATP synthase

A
  • The enzyme ATP synthase is responsible for the
    production of ATP
  • ATP synthase is embedded in the inner
    membrane (cristae) of the mitochondria
  • It uses H + ions as an energy source to
    combine ADP molecules with phosphate ions
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5
Q

What is aerobic respiration

A
  • Aerobic respiration: when glucose is broken down in the presence of
    oxygen to form carbon dioxide, water, and ATP
  • Glucose + oxygen 🡪 carbon dioxide + water + ATP (36)
  • Occurs in the cytoplasm AND mitochondria
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6
Q

What are the three enzyme controlled pathways for aerobic respiration

A
  1. Glycolysis
  2. Krebs cycle
  3. Electron transport chain
  • Each glucose molecule fed into the aerobic respiration pathway
    produces approximately 36 ATP
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7
Q

What is glycolysis

A
  • Glycolysis: breakdown of glucose by
    enzymes
  • Occurs in the cytoplasm
  • One glucose molecule is broken down
    into two molecules of pyruvate (with
    three carbons each)
  • Glycolysis uses 2 ATP but produces 4
    ATP… so overall (net) 2 ATP are made
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8
Q

What is Krebs Cycle

A
  • Occurs in the fluid matrix of the
    mitochondria
  • The pyruvate molecules produced
    from glycolysis go through a complex
    series of enzyme-controlled reactions
  • Pyruvate is attached to an enzyme to
    form acetyl CoA
  • Acetyl CoA is used in the Krebs cycle to
    produce the electron carrier NADH
  • 2 ATP are made
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9
Q

What is the electron transport chain

A
  • This is where oxygen is needed for aerobic respiration
  • Occurs on the cristae of the mitochondria
  • NADH drops electrons off at the electron transport chain on the cristae
  • These electrons “power” the enzyme ATP synthase which produces
    huge amounts of ATP
  • 32 ATP are made
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10
Q

What is anaerobic respiration

A
  • Anaerobic respiration: when glucose is broken down into lactic acid
    and ATP (energy)
  • No oxygen is present, therefore less energy (2 ATP) is produced
    compared to aerobic
  • Glucose 🡪 lactic acid + ATP (2)
  • Occurs in the cytoplasm
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11
Q

What cycle does anaerobic respiration go through

A

Anaerobic respiration involves glycolysis too, but goes a different way
from there

  1. Glycolysis
  2. Fermentation (alcoholic or lactic acid)
  • Each glucose molecule fed into the anaerobic respiration pathway
    produces approximately 2 ATP
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12
Q

What is alcoholic fermentation

A
  • Occurs in plants, bacteria, and fungi
  • Pyruvate molecules produced in glycolysis cannot be sent to Krebs
    cycle due to lack of oxygen
  • The fermentation process does not produce any energy; it only exists
    to convert pyruvate and hydrogen molecules into the waste products
    ethanol and CO2
  • Ethanol produced is a toxic waste product that can only be removed
    very slowly
  • This limits how much anaerobic respiration an organism or cell can
    do, as they are limited by how quickly they can “process” the ethanol
    into something less harmful
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13
Q

What is lactic acid fermentation

A
  • Occurs in animals
  • Anaerobic respiration is used during short, high-intensity exercise,
    producing lactic acid (not ethanol) as a waste product
  • You breathe hard after intense exercise as oxygen is needed to convert
    the lactic acid to other waste products such as carbon dioxide and water
  • Build up of lactic acid causes muscle fatigue, which is why you need
    rest after an extreme workout
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14
Q

What are the advantages and disadvantages of aerobic respiration

A

Aerobic respiration makes lots of energy (36 ATP per glucose) BUT
takes lots of time, as we need to wait for oxygen to slowly diffuse into
the cells. The waste products of aerobic respiration are water and carbon
dioxide, which are not toxic and can be easily removed

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15
Q

What are the advantages and disadvantages of anaerobic respiration

A

Anaerobic respiration is very fast BUT makes very little energy (only 2
ATP per glucose) The waste products of anaerobic respiration are ethanol OR lactic acid
(and carbon dioxide) which are toxic and can harm/kill the organism

  • This form of respiration is not sustainable
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16
Q

What are the adaptations of mitochondria

A

Inner membrane folded to form
cristae which increase surface area,
allowing for increased rate of
transport, therefore increased ATP
production (site of ATP production)

  • Fluid matrix surrounds the inner
    membrane which contains
    enzymes essential for respiration
  • It also contains ribosomes and
    genetic information to produce
    enzymes needed for respiration
    and make more mitochondria
17
Q

What are the adaptations of the outer membrane of the mitochondria

A
  • Outer membrane is selectively
    permeable; it only allows molecules
    crucial to respiration to move in and
    out, such as oxygen, glucose, and
    carbon dioxide
  • Outer membrane allows for
    mitochondria to be separated from the
    cytoplasm, helping create the
    optimum environment for respiration’s
    enzymes (about 50°C)
18
Q

How is temperature a factor affecting respiration

A

Changing temperature causes changes in enzyme activity

  • Respiration rate is highest at optimum temperature
  • Enzymes denature once the optimum temperature has been
    exceeded
19
Q

How does changing the availability affect respiration

A

Changing the availability of reactants changes rate of respiration

  • If the glucose supply in the cell / blood is low (e.g. high intensity
    exercise, between meals, starvation), less ATP is produced causing
    fatigue and dizziness
  • If the oxygen supply is low, cells will try to use anaerobic respiration
    to continue making ATP which is faster but short-lived and less
    efficient
20
Q

How does changing the energy affect respiration

A

Changing the cell’s energy demands changes rate of respiration

  • Different cells demand different energy (e.g. fat cell vs sperm cell)
  • Increasing energy demand due to increased cell activity (e.g. leg
    muscle cells while running)
  • Increasing energy demand due to change in cell state (e.g. a cell in
    mitosis will need more energy)