Cellular Respiration Flashcards
Aim of cellular respiration
Refers to the biochemical pathways that release energy from glucose
Energy from glucose
Energy released from glucose through cellular respiration is used to generate the coenzyme ATP
What happens when a cell needs energy?
High Energy bond in ATP is broken and the phosphate is removed, releasing the energy stored in the bond
Catabolic
Larger/complex compounds are broken down into simpler ones. Energy is also released
Exergonic
When energy is released
ADP to ATP
Cells can store excess energy by adding an Pi to the ADP, storing the energy in the bond, forming ATP once again
Anabolic
Smaller compounds make larger compounds. Energy is needed
Endergonic
When energy is required or is stored in a bond
NAD+
-> A coenzyme
-> Is a energy carrier
-> In ETC, NADH –> NAD+ and the energy released are used in the formation of ATP
FAD/FADH2
-> A coenzyme
-> Energy carrier
-> In Krebs: FAD ->FADH2
-> In ETC: FADH2 –> FAD and the released energy is used to make ATP
2 types of Cellular respiration
- Anaerobic (oxygen absent )
- Aerobic (oxygen present)
Aerobic Respiration
- Glucose is broken down in the presence of oxygen and is produces CO2 and H2O
- Includes Krebs and ETC ( both occur in mitochondria )
Anaerobic Respiration
- Products formed depend on the type of organism this process occurs within.
- Plants and yeast carry out Alcohol fermentation:
glucose –> ethanol + CO2 + 2 ATP - Animal carry out lactic acid fermentation
glucose –> lactic acid + 2 ATP
Glycolysis- Anaerobic
- Location: Cytosol of the cell
-Break down the large glucose molecules into 2 smaller molecules (Pyruvate)
Inputs: Glucose, 2 NAD+, 2 ADP + Pi
Outputs: 2 Pyruvate, 2 NADH, Net of 2 ATP
Pyruvate Oxidation
- Pyruvate are transported by Active Transport to the fluid matrix of the mitochondria
- Pyruvate –> 2 Acetyl CoA
- 2 NADH are produced and CO2 (Waste)
Krebs Cycle- Aerobic
- Location: Fluid matrix of the mitochondrion
- Is a series of biochemical reactions, each catalysed by a different enzyme
Inputs: 2 Acetyl-CoA, 2ADP+Pi, 2 NAD+, 2FAD+
Outputs: 2 ATP, 2NADH, 2FADH, 4CO2
- Contains many ribosomes due to the large number of enzymes required for the Krebs cycle
Electron Transport Chain
- Location: Inner membrane of the mitochondria, the (cristae)
- Overall purpose is to transport protons ( H+ ions) and electrons across a membrane (cristae) as a system for generating ATP
Inputs: NADH, FADH2, ADP + Pi, O2
Outputs: NAD+, FAD+, 26 OR 28 ATP, H2O - The more cristae there are, the more surface area there s available for carrying out the reactions of the electrons transport chain
Aerobic Respiration Equation
C6H12O6 +6O2 –> 6CO2 +6H2O + 30 OR 32 ATP
What makes up the ETC
In the inner membrane of mitochondria, there are protein complexes including enzymes and cytochromes which are embedded. They form an interconnected series.
Number of ATP produced for each stage
Glycolysis: 2 ATP
Krebs: 2 ATP
ETC: 26 or 28 ATP
Total Aerobic Yield: 30 or 32 ATP
Anaerobic Respiration
- Is far less efficient than aerobic cellular respiration
- Begins with the breakdown of glucose into pyruvate forming 2 ATP
Lactic Acid Fermentation
Location: Cytoplasm
- Through glycolysis, glucose is broken down into 2 pyruvate further broken down into lactic acid
Inputs: ADP + Pi, Glucose, NAD+
Outputs : 2 ATP, NAD+ , Lactic Acid
Ethanol Fermentation
Location: Cytosol
- Through glycolysis, glucose is broken down into 2 pyruvate further broken down into ethanol and CO2
Inputs: ADP + Pi, Glucose, NAD+
Outputs: 2 ATP, NAD+, Ethanol, CO2
Temperature affecting cellular respiration
- Temperature: When temp is below opt there is low kinetic energy= low cellular respiration = enzymes become inactivated due to lose of flexibility in the bonds at the active site making it unable to bind to substrates
–> Optimal temp is when max rate of cellular respiration
Glucose availability affecting cellular respiration
–> All chemical reactions are limited by the concentration of reactants
–> Glucose is the substrate for glycolysis, therefore the availability of glucose will affect the rate at which this first occurs.
Increased glucose availability = increased rate of cellular respiration
Oxygen Concentration affecting cellular respiration
-> If oxygen availability is low = rate will decrease
–> When oxygen concentration is low, cells stop aerobic and begin anaerobic cellular respiration
–> HIgh oxygen concentrations will increase the rate of aerobic respiration and decrease the rate of anaerobic respiration