Cellular level Flashcards
How h2o levels in body influence thirst cycle
Water leaving body as exhaled air, sweat or urine trigger thirst response. Decrease in plasma volume ^ plasma osmolarity stimulates thirst center( hypothalamus)
Causes of edema
1. excess accumulation of water.** 2**. underlying med conditions- drugs, pregnancy, injury, allergic reaction. kidney damage, CHF
symptoms of edema
swelling sub q- ^ limb size, stretched tight skin, pulmonary edema, damage to blood vessels
Main route of water loss
- urine 2. kidneys 3. skin
Bicarbonate
tubular cells conserved not reabsorbed in kidney
Chloride
**predominant Extracellular anion
Hypo(na)tremia
**level of (sodium) in blood is too low- body is holding too much water
symptoms of ^ sodium
sweating vomiting, diarrhea, diabetes
CHF (symptoms)
Hypernatremia = ^sodium
hypo/hyperkalemia = potassium decreased or increased
Hypo/hyperchloremia= Chloride decreased/increased
6 most important electrolytes
sodium, potassium chloride, bicarbonate, calcium, phosphate
protein channel movement solutes
allow transport across membrane using less energy or **Weakly
6 ions for body function
sodium, chloride, potassium, bicarbonate, calcium, phosphate
dehydration
net loss of water= insufficient in blood & tissues.
caused by lack of water. Produce dark urine
PH too low
metabolic acidosis when bicarbonate is too low
alkalosis
elevated bicarbonate in excess>7.45