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A Dent Board Exam Reviewer 📒 > Cellular Junctions > Flashcards

Cellular Junctions Flashcards

1
Q

” Spot-weld like” / macula adherens attaches cells of the same type

A

Desmosomes

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2
Q

Attaches cells of the same type

A

Hemidesmosomes

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3
Q

Seen between epidermis and between cardiac muscle cells

A

Desmosomes

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4
Q

Seen between epidermal cells and basement membrane,
Also found between functional epithelium and tooth surface

A

Hemidesmosomes

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5
Q

Destruction of the epidermal desmosomes

A

Pemphigus vulgaris

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6
Q

Histological features of pemphigus vulgaris

A

Nikolsky sign

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7
Q

Separation of the epithelial cells

A

Acantholysis

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8
Q

Sloughing off of the skin; rub off of tissues

A

Nikolsky sign

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9
Q

Other epidermal diseases associate with nikolsky sign

A
  1. Toxic epidermal necrolysis
  2. Steven jhonsons
  3. Staphylococcal scalded skin syndrome ( SSSs)
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10
Q

Epidermal disease associated with hemidesmosomes

A

Bullous Pemphigoid

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11
Q

Histological features of hemidesmosomes

A

Subepidermal non-acantholytic blisters

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12
Q

Seen in cardiac muscle cells and epidermis

A

Desmosomes

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13
Q

Seen in epidermal cells and basement membrane

A

Hemidesmosomes

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14
Q

Seen in nerve cell and cardiac muscle cells

A

Gap junctions

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15
Q

“Zona occludens”

A

Tight junctions

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16
Q

Skin

A

Adherens junction

17
Q

Formed by claudins, occludins

A

Tight junctions

18
Q

Heart

A

Gap junctions

19
Q

In infected cells: it sends cytokines to neighboring cells triggering apoptosis preventing infectious spread ( bystander effect )

A

Gap junctions

20
Q

In tight junctions,——— are the proteins that hold cells tightly together

A

Claudins

21
Q

——- are channels between cell which allow for transport of substances including ions and water

A

Gap junction

22
Q

Are formed bygroups of proteins that anchor cells together side by side. Connecting the actin skeletons of each

A

Adherens junction

23
Q

Are cell junctions that keep adjacent epithelial cells together using proteins that extend across the membrane and to the intermediate filaments within the cells

A

Desmosomes

24
Q

Are connections between cells that form a watertight seal between cells

A

Tight junctions

25
Q

Gap junctions are formed by membrane protein called

A

Connexins

26
Q

Are proteins that attach the actin cytoskeletons or adjacent cells to one another

A

Cadherins

A Dent Board Exam Reviewer 📒 (3 decks)

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