cellular injury Flashcards

0
Q

acute ischemia results in :

A

injusry

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1
Q

slowly developing ischemia results in :

A

atrophy

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2
Q

what are common causes of cellular injury?

A

inflammation, nutritional deficiency or excess, hypoxia, trauma, and genetic mutations

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3
Q

what is hypoxia?

A

low osygen delivery to tissue

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4
Q

what is ischemia?

A

restriction in blood supply to tissues, causing a shortage of oxygen and glucose needed for cellular metabolism

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5
Q

who is the final electron acceptor in the electron transport chain of oxidative phosphorylation?

A

oxygen

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6
Q

what are some causes of hypoxia?

A

ischemia, hypoxemia, and decreased O2 carrying capacity of blood

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7
Q

ischemia arises with:

A

decreased arterial perfusion, decreased venous drainage, shock - generalized hypotension resulting in poor tissue perfusion

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8
Q

what is hypoxemia?

A

low partial pressure of oxygen in the blood (PaO2 < 90%)

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9
Q

hypoxemia arises with:

A

high altitude, hypoventilation, diffusion defect, V/Q mismatch

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