Cellular Biology Flashcards

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1
Q

What are the structural levels of the body?

A

Organelle = Subcellular structure made of molecules to perform specific job.
Cell = Smallest + most numerous structural + functional unit of life.
Tissue = group of cells with a similar structure that operate together as a unit.
Organ = structure made up of multiple types of tissue to perform a specific function.
System = tissues and organs that work together to perform a complicated task.

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2
Q

What is a cell?

A

The smallest structural + functional unit of life. Chemical reactions (metabolism) take place in the cell + where genome stored.

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3
Q

What are the roles of each system of the body?

A

Endocrine = Secrete chemical messengers into the blood.
Nervous = Transit messages between the brain and the rest of the body.
Respiratory = Supply oxygen to the blood and remove carbon dioxide.
Circulatory = Transport chemical messengers, respiratory gases, product of digestion, blood cells and waste round the body by pumping blood.
Digestive = Transfer nutrients to the body and absorb water whilst eliminating waste.
Integumentary = Regulates body temp. reduces water loss + protects the body from damage.
Lymphatic = Protect the body from infection.
Reproductive = Produce new life.
Urinary = eliminate waste products + preserve chemical and water balance.
Muscular = enable motion + thermal generation + push food through tract + pump heart.
Skeletal = enable motion when muscles contract.

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4
Q

What is the nucleus (S+F)?

A

Nucleus = the control centre of the cell.
Nucleoplasm = Thick liquid suspension - enables transportation + preserves shape and structure.
Nuclear envelope = Pored double membrane - separates contents + enables passage of some molecules.
Chromatin = DNA wound around histone proteins - Tightly coiled for storage + spreads out for division.
Nucleolus = Stores RNA to make ribosomes.

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5
Q

What are ribosomes (S+F)?

A

Free floating or attached to the Rough ER - Site of protein synthesis.

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6
Q

What are mitochondria (S+F)?

A

Rod or spherical shaped + folded inner membrane - Surface area (up) for aerobic respiration.

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7
Q

What is the Smooth ER (S+F)?

A

System of membranes with no ribosomes with surface area (up) + fluid filled cavities - Transport + synthesis + storage of carbohydrates and lipids.

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8
Q

What is the Rough ER (S+F)?

A

System of membranes studded with ribosomes with surface area (up) + fluid-filled cavities - Storage + transport + synthesis of proteins.

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9
Q

What is the Golgi apparatus (S+F)?

A

Stack of membrane-bound flattened sacs to and from which vesicles transport substances - Packages, modifies and transports proteins + lipids. Creates lysosomes.

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10
Q

What are lysosomes (S+F)?

A

Vesicles of membrane + contain hydrolytic enzymes (lysozymes) - breaks down cells in phagocytosis.

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11
Q

What is the Permanent vacuole (S+F)?

A

Fluids + sugars + amino acids stored and supports the cell when turgid.

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12
Q

What is the Cytoskeleton (S+F)?

A

Formed of (Tubulin tubes) microtubules + (Thread like Structural protein) filaments - Shape and strength to cell + transports organelle throughout the cell + anchors organelles..

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13
Q

What is the role of the plasma membrane?

A

Stop damaging particles entering and keep cytoplasm in + boundary between cell and environment + enable some molecules to pass through such as respiratory gases and nutrients.

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14
Q

What is the structure of the plasma membrane ?

A

Phospholipid heads are hydrophilic + tails are hydrophobic so form a phospholipid bilayer so small, polar molecules can pass through. Cholesterol regulates the fluidity of the bilayer.
Integral proteins (inserted into membrane) (Transport) of substances in and out through pumps or channels.
(Receptors) enable cells to recognise familiar or foreign cells.
Peripheral proteins (outside surface) -
Part of extracellular surface, surrounding + supporting cell or part of cytoskeleton on inside surface.

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15
Q

What are centrioles (S+F)?

A

Tubulin subunits at right angles to each other - form spindle fibres + found in centromeres.

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16
Q

What are the features of prokaryotic and eukaryotic cells?

A

(Eukaryotes) Jelly-like cytoplasm + nucleus + membrane-bound organelles + plasma membrane.
(Prokaryotes) Cytoplasm + no nucleus + no membrane-bound organelles + plasma membrane.

17
Q

What is facilitated diffusion + the factors affecting it?

A

(Facilitated diffusion) = Solute particles’ net movement from a region of high concentration to a region of low concentration through channel + carrier proteins (e.g. glucose + amino acids).
Channels - pores for charged particles.
Carriers - molecules bind + shape change + release.
(Factors) - no. channel or carrier proteins + steepness of concentration gradient.

18
Q

What is diffusion + the factors affecting it?

A

Solute particles’ net movement from a region of high concentration to a region of low concentration. (e.g. small + non polar such as oxygen and carbon dioxide).
(Factors) - Surface area + thickness of exchange surface + steepness of concentration gradient.

19
Q

What is is osmosis + the factors affecting it?

A

Water particles’ net movement across a partially permeable membrane from a region of high concentration to a region of low concentration.
(Factors) - Surface area + thickness of exchange surface + steepness of concentration gradient.

20
Q

What types of solutions are there?

A

Isotonic = Same concentration of water on each side of the membrane.
Hypertonic = high solute conc. outside cell.
Hypotonic = high solute conc. inside cell.

21
Q

What is active transport + the types of membrane proteins + the factors affecting it?

A

Particles’ net movement across a partially permeable membrane from a region of low concentration to a region of high concentration using energy.
(Transport Pumps) = Molecules bind, shape changes + released and ATP splits into ADP + Pi.
(Co-transporters) = molecules bind + 1 molecule’s concentration gradient used to transport the other molecule against its concentration gradient.
Factors - Speed of transport pumps + no. transport pumps + ATP availability.

22
Q

What is the structure and function of deoxyribonucleic acid (DNA)?

A

Shape of double helix polymer + formed of nucleotides that stores info. for the synthesis of proteins through encoding genes.

23
Q

What are the pairs of bases in DNA?

A

Thymine - adenine + cytosine - guanine.

24
Q

What is the structure and function of ribonucleic acid (RNA)?

A

Shape of single helix + formed of nucleotides that transfers info. to the ribosomes.

25
Q

What are the pairs of bases in RNA?

A

Uracil - adenine + cytosine-guanine.

26
Q

What is a gene?

A

Segment of DNA molecule that codes for a trait though the synthesis of 1 RNA molecule.

27
Q

What is a chromosome?

A

A single thread-like DNA molecule wound around proteins.

28
Q

What is the process of transcription?

A

Transcription factor binds to promoter region (recruiting RNA + enzymes) - helicase unzips DNA by breaking H bonds forming a template strand + coding strand - RNA polymerase binds just before the START codon + passes along the strand - RNA nucleotides pair up with bases on the template strand - Sugar-phosphate groups bonded together - Pre-mRNA molecule formed when enzyme reaches STOP codon.

29
Q

What is the process of translation?

A

tRNA molecule binds to a specific amino acid - tRNA anticodon pairs with codon on mRNA at ribosome - peptide bond formed between two amino acids - synthesis of chain finished when STOP codon reached.

30
Q

What is the process of semi-conservative DNA replication?

A

The enzyme helicase breaks the H bonds between the nucleotides so two strands formed - Each original strand is a template for free floating DNA nucleotides to attach - DNA polymerase joins the nucleotides of the new strands together - Each new DNA molecule has an original strand + a new strand.

31
Q

What is prophase?

A

Nuclear envelope disappears + sister chromatids join at a centromere to form chromosomes. The centrioles move towards the two poles of the cell where spindle fibres form between them.

32
Q

What is metaphase?

A

Chromosomes line up so each chromatid faces respective pole + joins to spindle fibre.

33
Q

What is anaphase?

A

Centromere splits to form two chromosomes + each chromosome pulled towards pole to form two pools of genetically identical info.

34
Q

What is telophase?

A

Nuclei reform + DNA restored to original form + location.

35
Q

What is cytokinesis?

A

The cell splits into two.

36
Q

What is the similarities and differences between mitosis and meiosis?

A

(Similarities) - Each undergo PMAT + types of cell division.
(differences) - Mitosis = somatic cells + 1 division + 2 daughter cells + 46 chromosomes + genetically identical.
Meiosis = gametes + 2 divisions + 4 daughter cells + 23 chromosomes + genetically different.