Cells/Organ Systems/Skeletal System/Muscular System Flashcards

1
Q

What are the four major types of tissues found in the body? Where would you find them?

A
  • Epithelial: sheets of cells that line or cover various surfaces and body cavities (skin/lining of mouth/digestive tract/lungs/bladder/kidney tubules)
  • Connective: supports the softer organs of the body/connects parts of the body together (diverse in where they are located)
  • Muscle: cells that are specialized to shorten or contract resulting in movement of some kind (heart, skeletal muscle of tendons, smooth muscle of hollow organs
  • Nervous: specialized for generating and transmitting electrical impulses throughout the body (brain, spinal cord, nerves)
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2
Q

Structure/Location/Function of each tissue discussed in class

A
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3
Q

How can you differentiate one tissue type from another?

A

-by the type of cells it contains

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4
Q

Difference between an endocrine and an exocrine gland

A
  • Endocrine Glands: secrete products (hormones) into the blood for distribution throughout the body
  • Exocrine Glands: secrete products into hollow organs or ducts (glands of mouth that secrete saliva and skin that secretes sweat)
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5
Q

What kind of fibers are found in connective tissue/what are their characteristics & functions?

A
  • Collagen Fibers: made of protein/confer strength
  • Elastic Fibers: made primarily of elastin/can stretch without breaking
  • Reticular Fibers: made of collagen/internal structural framework for soft organs like the liver, spleen, lymph nodes
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6
Q

What are the components of blood?

A
  • WBCs: immune defense
  • RBCs: transport oxygen and nutrients and waste products of cells metabolism
  • Platelets: participate in clotting process
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7
Q

What are the major cavities of the body/location/organs that are in each?

A

Anterior Cavities

  • Abdominal Cavity- stomach area/ contains digestive organs, kidneys, liver etc.
  • Pelvic Cavity- groin area/ contains bladder
  • Thoracic Cavity- chest area/contains heart and lungs

Posterior Cavities

  • Cranial Cavity- head/contains brain
  • Spinal Cavity- the back/ contains the spine
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8
Q

What are the two layers of the skin and what types of cells/ extracellular materials are found in each?

A
  • Epidermis: outer layer of epithelial tissue, stratified squamous epithelial cells
    keratinocytes: provide tough waterproof protein (keratin)
    melanocytes: give skin its pigment (melanin)
  • Dermis: inner layer of connective tissue/supports tissues
    fibroblasts: produces collagen and other fibers

mast cells: releases histamine during inflammatory responses

wbcs

fat cells

collagen&elastin fibers for strength and elasticity

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9
Q

What are the functions of the skin?

A
  • protection from dehydration
  • protection from injury
  • defense against invasion by bacteria and viruses
  • regulation of body temperature
  • synthesis of vitamin D
  • sensation
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10
Q

What are the major types of cell junction/what function does each perform?

A
  • Tight Junctions: seal the plasma membrane tightly together (digestive tract lining/bladder lining)
  • Adhesion Junction/Spot Desmosomes: permit some movement between cells/allow tissues to stretch and bend (skin)
  • Gap Junction: protein channels enable movement of materials between cells
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11
Q

What are cell junction constructed of?

A

-proteins

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12
Q

How is homeostasis maintained in the body?

A

-by negative feedback where deviations from the desired conditions are automatically detected and counteracted

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13
Q

Positive & Negative Feedback

A

Positive Feedback: change in controlled variable causes a series of events that amplifies original change (ex. childbirth)

-not a mechanism for maintaining homeostasis

Negative Feedback: deviations from normal are detected and counteracted (ex. homeostasis of body temperature

control variable, sensor, control center, effector

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14
Q

Four components of negative feedback system/function of each:

A
  • Controlled Variable: any physical or chemical property that might vary from time to time and must be controlled to maintain homeostasis
  • Sensor: monitors current value of controlled variable and sends info to control center
  • Control Center: receives input from the sensor and compares it to the correct, internally set value of the controlled variable
  • Effector: takes necessary action to correct the imbalance
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15
Q

The 11 Major Body Systems and their Functions:

A

Muscular: generates heat/produces movement

Urinary: maintains volume of body fluid/excretes waste

Respiratory: exchange gases/produce sound

Digestive: provides body with water and nutrient

Endocrine: produces hormones that regulate body functions/integrative functions

Reproductive: egg, sperm, genitals

Skeletal: protects, supports, stores minerals, produces blood cells

Lymphatic: returns excess tissue fluid to circulatory system, defense responses

Integumentary: protects from injury, infection, dehydration/ receives sensory input

Nervous: detects external and internal stimuli

Circulatory: transports materials to and from cells

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16
Q

Four Types of Tissue Membranes (location/function)

A
  • Serous: line and lubricate internal body cavities/reduce friction between organs
  • Mucous: lines airways, digestive tract, reproductive tract/lubricate surface, capture debris
  • Synovial: line spaces in movable joints/lubricate the joint
  • Cutaneous: form outer covering (skin)
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17
Q

What is the structure of compact and spongy bone?

A

Compact Bone: forms shaft and ends/ contains marrow space

Spongy Bone: trabeculae form lattice like supports/spaces may contain red bone marrow

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18
Q

What are the cells you find in bone tissue?/What do they do?

A
  • Osteoblasts: young bone forming cells
  • Osteoclasts: bone dissolving cells
  • Osteocytes: mature bone cells
19
Q

How does a fracture heal?

A
  • After a fracture blood vessels supplying the bone bleed into the area producing a mass of clotted blood called a hematoma
  • Fibroblasts migrate to the area for repair/some of them become chondroblasts and together they produce a fibrocartilage bond called a callus
  • Osteoclasts arrive and remove dead fragments of bone and blood cells from the hematoma
  • Osteoblast arrive and start the deposit of new bone (osteoid matrix)
20
Q

What are the major bones of a skeleton?

A
  • Long (limbs and fingers)
  • Short (wrist bones)
  • Flat (cranial, sternum, ribs)
  • Irregular (coxal bone, vertebrae)
21
Q

***Process of bone formation (ossification) in the fetal skeleton

A

Early Fetal Development: cartilage model forms/formed by chondroblasts (cartilage forming cells)

Later Fetal Development: osteoblasts replace cartilage with bone

Childhood: primary and secondary ossification sites are formed

Adolescence: elongation of growth plates

22
Q

How do bones increase in length?

A
  • bones increase in length by growth plates( where chondroblasts and osteoblasts remain active)
  • deposition of new cartilage is concentrated on the outside of the plate/ conversion of cartilage model to bone is concentrated on the inside of the plate
23
Q

What is bone remodeling?

A

Bone Remodeling: changes in shape, size, and strenght

  • dependent on diet, excercise, age
  • weight bearing exercise increases overall bone mass and strength
24
Q

What bones make up the appendicular and axial skeleton?

A

Appendicular: bones of the appendages and their attached structures

-pectoral girdle, arms, pelvic girdle, legs

Axial: midline of the body

-skull, sternum, ribs, vertebral column

25
Q

What are the regions of the spinal column?/How many bones are in each region?

A

Cervical(neck): 7 vertebrae

Thoracic(chest): 12 vertebrae

Lumbar(small of back): 5 vertebrae

Sacral(sacrum): 5 fused vertebrae

Coccygeal(coccyx): 4 fused vertebrae

26
Q

How can you identify cervical, thoracic, and lumbar vertebrae?

A
27
Q

Different types of joints/Location

A
  • Fibrous: immovable (joints between flat bones of skull)
  • Cartilaginous: slightly movable (joints between adjacent vertebrae)
  • Synovial: freely movable (seperated by fluid filled cavity/ball and socket/hinge joint)
28
Q

Structure of Synovial Joint

A

Hinge Joint: movement in one plane (knee/elbow)

Ball and Socket: more free movement than hinge joint

  • to reduce friction there are disks of cartilage on either side of the knee called menisci/bursae which are sacs of fluid add more cushioning
  • synovial membrane secretes synovial fluid as lubricant
  • hyaline cartilage acts as cushion

Joint Capsule: synovial membrane and hyaline cartilage

Tendons: join bone to muscle

29
Q

How many and what kind of ribs are there?/Which bones are ribs attached to?

A
  • there are 12 pairs of ribs
  • 10 pairs are attached to the vertebrae in the back, sternum in the front
  • lowest 2 pairs are floating (attached to vertebrae but not sternum)
30
Q

Diseases/Injuries of the skeleton and joints

A

Sprains: stretched or torn ligaments/heal slowly

Bursitis & Tendonitis: inflammation of the bursae or tendons

Arthritis: inflammation of joints

Osteoporosis: excessive bone loss

31
Q

What causes osteoporosis/how do you prevent it?

A
  • osteoporosis is caused by excessive bone loss
  • getting enough calcium and vitamin D/ working out consistently can prevent osteoporosis
32
Q

Skeletal, Cardiac, & Smooth Muscle

A

Skeletal Muscle: attaches to skeleton/provides strength & mobility

Cardiac Muscle: in the heart

Smooth Muscle: digestive tract, blood vessels, uterus, ureters

33
Q

Structure of skeletal muscle

A
  • Muscle Cell(fiber): contains many individual myofibrils
  • Myofibril: cylindrical structures arranged in parallel
  • Actin Thin Filament
  • Myosin Thick Filament
  • Sarcomere: segment of myofibril from one z line to the next
  • Z-line
  • Fascicle: bundles of muscle
34
Q

Structure of skeletal muscle (contd.)

A
  • Sarcoplasmic Reticulum: membrane bound chambers
  • Troponin:
  • Tropomysin: protein involved in muscle contraction
  • T-tubule: tubelike extensions of the cell membrane
35
Q

How are muscles innervated/what is a motor unit?

A

-Muscle cells are innervated by a single motor axon

Motor Unit: motor neuron and all the muscle cells it controls/smallest functional unit of a muscle contraction

36
Q

What is a sarcomere/what components make up a sarcomere?

A

Sarcomere: contractile unit of muscle

  • myosin: thick filament
  • actin: thin filaments
37
Q

What role does calcium play in muscle contraction?

A
  • presence of calcium permits contractions
  • calcium must be present for cross-bridges to form
38
Q

Process of muscle contraction

A

Motor neurons stimulate muscle contraction

Acetylcholine is released from motor neuron at

neuromuscular junction

Electrical impulse is transmitted along T tubules

Calcium is released from sarcoplasmic reticulum (modified smooth endoplasmic reticulum)

Calcium initiates chain of events that cause contraction

1.

Calcium is released from sarcoplasmic reticulum

2.

Calcium binds to troponin

3.

Troponin–tropomyosin complex shifts position

4.

Myosin binding site is exposed

5.

Myosin heads form cross-bridges with actin

6.

Actin filaments are pulled toward center of

sarcomere

7.

Sarcomere shortens

39
Q

Define Muscle Twitch/Summation/Recruitment

A

Muscle Twitch: small muscle contraction

Summation: occurs as successive stimuli are added together to produce a stronger muscle contraction

Recruitment: activation of additional motor units increases muscle tone

40
Q

Where does the energy come from for muscle contraction?

A
  • Stored ATP: direct energy source
  • Stored Creatine Phosphate: converted to ATP
  • Stored Glycogen: depends on whether oxygen is available/ 2 ATP in absence of oxygen, 36 in presence
  • Aerobic Metabolism: complete metabolism of one glucose molecule/ yields 36 ATP
41
Q

Slow Twitch & Fast Twitch Muscle

A

Slow Twitch: contract slowly, make ATP by aerobic metabolism, many mitochondria, well supplied with blood vessels, store very little glycogen, red muscle, used for endurance activities

Fast Twitch: contract quickly, rapidly break down ATP

fewer mitochondria, little or no blood vessels, store a lot of glycogen, white muscle, capable of anaerobic metabolism, used for brief high intensity activties

42
Q

How does frequency of stimulation influence muscle contraction?

A

When the stimulation frequency was increased to the point in which muscle relaxation did not occur the amount of force progressively increased with each stimulus. When muscle twitches overlap, no muscles relax, and stimuli occurs one after another in a short amount of time, the muscle contraction is higher than if a single stand alone contraction had occurred; also known as wave summation.

43
Q

How does contraction of smooth muscle different from skeletal and cardiac muscle?

A

Skeletal muscle: fastest

Cardiac muscle: moderate

Smooth muscle

Very slow

Partially contracted all of the time

Almost never fatigues

44
Q

Muscular Disorder and Disease

A

-Muscular Dystrophy:

Genetic disease: Duchenne muscular dystrophy

Modified dystrophin protein enables leakage of Ca

++ into cells

Extra Calcium activates enzymes that destroy muscle

proteins

Muscle weakening and wasting

Muscle mass is replaced with fibrous connective

tissue

Life expectancy: approx. 30 years

  • Tetanus: infection of deep wound by bacteria/ causes muscle to contract forcefully
  • Muscle Cramps: caused by dehydration and ion imbalances
  • Fasciitis: inflammation of fascia