Cells of the NS Flashcards
Why can’t neurones be classified?
- very polymorphous nature (exists in different forms etc.)
- heterogenous morphology (each 1 is somewhat unique)
- hard to classify by shape, location + function
What is a mature neurone?
non-dividing (?) excitable cell
What is the main function of a mature neurone?
recieve + transmit info in form of electrical signals
What is defining feature of unipolar neurones?
1 axonal projection
What is the defining feature of pseudo-unipolar neurones?
1 axonal projection that divides into 2
What is defining feature of bipolar neurones?
2 axonal projections from cell body
What is defining feature of multipolar neurones?
1 axonal projection + multiple dendrites from cell body
What are 3 examples of multipolar neurones?
- purkinje
- golgi
- pyramidal
What is a pyramidal cell?
multipolar neurone w/ ‘pyramid’ shaped cell body
What is a golgi cell?
GABA mulitpolar neurons found in the cerebellum
What is a purkinje cell?
GABA mulitpolar neurons found in the cerebellum
What are 3 similar features found in most neurones?
- soma
- axon
- dendrites
What is a soma?
- cell body, perikaryon
* contains nucleus, ribosomes + neurofilaments for structure + transport
What is an axon?
- Long process (aka nerve fibre) - originates from soma at axon hillock
- Can branch off into ‘collaterals’
- Usually covered in myelin
What is a dendrite?
- highly branched part of cell body
- NOT covered in myelin
- receives signals form other neurones
What is an axon hillock?
area of axon projection
What are the 6 main cells of the CNS?
- neurones
- oligodendrocyte
- astrocyte
- microglia
- ependyma
- schwann cell
What is an oligodendrocyte?
- glial cell
- produces myelin in CNS
- sends out numerous projections to form internodes of myelin covering axons of neurones
- capable of myelinating a no. of axons
What is a Schwann cell?
- myelin producing cells of PNS
* can only myelinate single axonal segment
What is a microglia?
- similar to macrophages
* performs immune functions of CNS
What is an ependyma?
- epithelial cells
- lines fluid-filled ventricles
- regulates production + movement of CSF
What is an astrocyte?
- most abundant cell type in the brain
- structural cells
- roles in cell repair, synapse formation, neuronal maturation + plasticity