Cells of the Nervous System Flashcards

1
Q

What parts of the body are in the Central Nervous System (CNS)?

A

The brain and the spinal cord

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What region refers to the Peripheral Nervous System (PNS)?

A

This system makes up all of the nerves which extend from the spinal cord.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What are the three primary functions of neurons?

A

· Receive information
· Conduct information
· Transmit information

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

How many types of neurons are there?

A

There are more than 10,000 types of this cell.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

The electrical signals exchanged between nueral cells refer to the passage of what particle group?

A

Ions are used for this method of communication!

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What are the three functional regions of a “typical” neuron?

A

Input (receiving)

Conducting

Output

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What structures are found within the input region of a typical neuron?

A

This region of the neuron contains pre-synaptic fibers, dendrites, the cell body, and the nucleus.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What structures are found within the ‘conducting’ region of a typical neuron?

A

Axons (nerve fibers), myelin and Nodes of Ranvier make up this region of the typical neuron.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What structures are found within the ‘output’ region of a typical neuron?

A

This region of the typical neuron contains synaptic boutons and terminal branches.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What is the Nissl Substance of a neural cell?

A

These intracellular structures are unique to neural cells; granular bodies made of polyribosomes and an expanded rER

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Why are neurons known the have large nucleoluses?

A

Neurons are largely secretory cells, undergoing very frequent transcription, therefore they have large…

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What two cellular structures can be found at the base of dendrites?

A

The rER and sER can be found at the base of these neural structures

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What cellular organelles can be found within dendrites?

A

Mitochondria, free ribosomes, microtubules and microfilaments are found in this cellular structure

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What is another word used to refer to the cell body?

A

Soma is another term used to refer to the…

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What are dendritic spines and what purpose do they serve?

A

Dendritic spines are tiny, numbered protrusions from dendrite branches which each facilitate a unique synaptic connection with the cell it interacts with

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What two features can dendritic spines be indicative of?

A

These structural features can be indicative of the frequency of a neuron’s input activity and of the presence/absence of neural disease

17
Q

What are the 4 parts which make up an axon?

A
  1. Initial segment (axon hilock)
  2. Axon process
  3. Synaptic boutons
  4. Growth cones (from synaptic boutons)
18
Q

What accomplishment is attributed to Ramon y Cajal?

A

This figure first used silver staining techniques to observe embryonic specimens

19
Q

Where can a growth cone be found on a neuron?

A

Growth cones can be found at the output end of the axon

20
Q

What are the 3 domains of a growth cone?

A
  1. thin fan sshaped sheet at the tip (lamellipodia)
  2. many thin spikes radiating forward (filopodia)
  3. Peripheral domain
  4. Transition domain
  5. Central domain
21
Q

How do growth cones relate to synaptic boutons?

A

Once growth cones have reached the target cell, they differentiate into synaptic boutons

22
Q

What are filopodia on growth cones?

A

On growth cones, these are many thin spikes radiating forward

23
Q

What are lammellipodia on growth cones?

A

On growth cones, this is a thin fan shaped structure at their tip

24
Q

What is contained in the peripheral domain of a growth cone?

A

Lamellipodia and fillopodia

25
What is contained in the Transition domain of growth cones?
This is the transition between the P and C domains
26
What is contained in the Central domain of a growth cone?
A think region containing organelles and vesicles
27
What are the three stages of axon growth?
1. Protrusion 2. Engorgement 3. Consolidation
28
Briefly describe the first stage of axonal growth.
Protrusion; rapid extensions of filopodia / thin lamellae containing actin
29
Briefly describe the second stage of axonal growth.
Engorgement: microtubules invade protrusions bringing vesicles and organelles
30
Briefly describe the third stage of axonal growth.
Consolidation: actin depolymerises in the neck of the growth cone, membrane shrinks forming cylindrical shaft
31
What is the length of a spinal motorneuron?
This type of neuron is 1mm — incredibly long by cellular standards!
32
What are the two types of signals which can activate a neural signalling pathway?
Chemical and physical signals
33
What are three examples of chemical signals that activate neural signalling pathways?
1. Growth factors (e.g.: Nerve Growth Factor) secreted by cells 2. Substrates (e.g.: laminin-1, fibronectin) 3. Other cells using adhesion receptors (eg: integrins, cadherins)
34
What are three examples of chemical signals that activate neural signalling pathways?
1. Tactile: if scratch surface, growth occurs along groove 2. Electrical 3. Photonic: light!
35
Name 8 major neurotransmitter substances.
1. Acetylcholine (ACh) 2. Noradrenaline 3. Adrenaline 4. Dopamine 5. 5-Hydroxytryptamine (5-HT, serotonin) 6. Gamma- aminobutyric acid (GABA) 7. Glycine 8. Glutamic acid