Cells of Immune system Flashcards

1
Q

Immune cells?

A

Cells which gives immunity

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2
Q

Property of IMMUNE CELLS?

A
  1. Ag Recognition
  2. Ag Neutralisation
  3. Ab Production
  4. Cytokine production
  5. Ab Bind
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3
Q

RBC & platelets doesn’t follow these properties:
1. Ag Recognition
2. Ag Neutralisation
3. Ab Production
4. Cytokine production
5. Ab Bind

True or False?

A

True

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4
Q

WBC has 2 types ____ & ____

A

Granulocytes &
Agranular

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5
Q

Granulocytes has 3 types____, ______ &_____

A

Neutrophil,
Basophil and
Eosinophil

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6
Q

Neutrophil, Basophil and Eosinophils are _______?

A

Polymorpho Nuclear Leukocytes. (PMNs)

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7
Q

Agranular has 4 types:

A

Monocytes,
B-Cell,
T-Cell &
NK Cell

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8
Q

Lymphocytes are

A

B-Cell,
T-Cell &
NK Cell

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9
Q

what is Lymphoid organ?

A

Lymphoid organs are specialized tissues that play crucial roles in the immune system by producing and housing lymphocytes, such as the lymph nodes, spleen, and thymus.

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10
Q

WBCs cell produce by?

A

Bone marrow (Reddish, connective tissue)

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10
Q

WBCs cell get Mature at?

A

Thymus,
Spleen &
Lymph Nodes

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11
Q

Thymus present at?

A

above the heart

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12
Q

Spleen present at?

A

Below the heart

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13
Q

Lymph Nodes present at?

A

Distributed in whole body

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14
Q

WBC present in Blood circulation?

A

2-5%

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15
Q

WBC present in Lymph Nodes & Spleen

A

95%

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16
Q

Hematopoiesis?

A

Hematopoiesis is the process of blood cell formation, primarily occurring in the bone marrow, where stem cells differentiate into various types of blood cells.

17
Q

Fetus development in first trimester (0-3 months)

A

Yolksac

17
Q

Hematopoiesis Region?

A

Bone Marrow

18
Q

Fetus development in 3-4 months

A

Liver

19
Q

Fetus development in third trimester (6-9months)

A

Spleen + Bone marrow

20
Q

After Birth

A

Only Bone marrow

21
Q

No. of RBC cells per 100 ml

A

5.5 million

22
Q

No. of WBC cells per 100 ml

A

5-12000

23
Q

No. of Platelets per 100 ml

A

1.5-4 lakh

24
Q

Life span of RBC cells?

A

120 Days

25
Q

Life span of WBC cells?

A

7 Days

26
Q

How to identify which cell is stem cell?

A

Unique protein is present, called as marker of the cell, Cluster of Differentiation.

27
Q

Cluster of Differentiation (CD)?

A

Membrane bound protein/glycoprotein responsible for identification.

28
Q

CDs On hematopoietic cells?

A

CD 34+
CD 38-
CD 59+

29
Q

Morula

A

totipotent

29
Q

Stem cells properties

A

Undifferentiated

Self-renewal

Assymetric division

30
Q

Blastocoel (Placenta + ICM)

A

Pluripotent

31
Q

ICM develop into

A

Ectoderm
Mesoderm
Endoderm

32
Q

Mesoderm develop into

A

Bone ———> Bone marrow—–> Hematopoietic stem cells

33
Q

Hematopoietic stem cells

A

Multipotent

34
Q

Adult stem cells?

A

Skin epidermis
Hair Follicular
Stomach

35
Q

Unipotent

A

Spermatocytes in Male

36
Q

Induced Pluripotent Stem cells?

A

Those adult cels that can be induced into Pluripotent Stem cells, are called as Induced Pluripotent Stem cells.

37
Q

what make a totipotent a totipotent, pluripotent to pluripotent and multipotent to a multipotent?

A

Genes

38
Q

genes for Pluripotent?

A

Oct 4
Nanog
Sox 2
PSTAT 3
Myc

39
Q
A