cells and tissues Flashcards
what are the 6 levels of structural organisation of the human body
- chemical
- cellular
- tissue
- organ
- system
- organism
description and examples of the structural levels
chem - building blocks eg. atoms join to form molecules
cellular - basic structural and functional units of body eg. cardiac muscle cells, nerve cells
tissue - group of cells work together to perform particular function (4 classes = epithelial, connective, muscle, nerve) eg. cardiac muscle
organ - structures w/ specific funtions made of 2 or more types of tissues eg. heart, stomach, skin, brain
system - related organs w/ common funtion eg. cardiovascular
organismal - all parts functioning together to constitute living organism
11 body systems are…
- INTEGUMENTARY
- MUSCULAR
- SKELETAL
- URINARY
- REPRODUCTIVE
- DIGESTIVE
- NERVOUS
- ENDOCRINE
- LYMPHATIC & IMMUNE
- CARDIOVASCULAR
- RESPIRATORY
integumentary systems components (organs) and functions
- CUTANEOUS MEM. (skin) epidermis and dermis - E = protects surface, deeper tissues, vit. D. D = feeds E, strength
- HAIR follicles & sebaceous glands - sensation, protection, lubrication, removes waste
- SWEAT GLANDS - thermor. breast tissue = modified sweat gland
- NAILS - stiffen & protect digits
- SENSORY RECEPTORS - sensation touch temp. pain etc
- HYPODERMIS - fat stores insulation
muscular system components and functions
• SKELETAL MUSCLES - skeletal movement, entrance & exit to D sys R sys U sys
- AXIAL MUSCLES - support & positioning of axial skele
- APPENDICULAR MUS - support & move brace limbs
- TENDONS AND APONEUROSES - translate contractile forces to tasks. T = muscles to bone. A - muscle to muscle connection
skeletal system components and functions
- BONES CARTILATE JOINTS - c = bone interfaces. types: hyaline (ribs) fibro-(disks)
- AXIAL skele - skull, cartilage, ligaments. protects brain & SC, sense organs. supports body weight (over lower limbs)
- APPENDICULAR - limbs and supporting bones & ligaments. internal support —> muscles can move axial skele
nervous system
- CNS - control centre short term control over other systems
- brain - complex integrative activities
- spinal cord - relay info to & from brain, less complex act. eg reflex arc
- special senses (CNS AND PNS except optic nerve - CNS) - sensory input to brain sight hearing smell taste equilibrium
- PNS - link CNS w other systems and sense organs
endocrine system
- PINEAL GLAND - brain, day & night systems
- HYPOTHALAMUS/PITUITARY - brain, control other endocrine glands, reg. growth, fluid balance
- THYROID + PARATHYROID GLANDS - throat, metabolic rate & calcium levels
- THYMUS - below thyroid, maturation of lymphocytes
- ADRENAL - top of kidneys. water & mineral balance, tissue metabolism, cardio and resp function (adrenaline)
- KIDNEYS - RBC production, calcium levels, BP up
- PANCREAS
- GONADS - sexual characteristics & reprod.
growth hormone effects
- pit. gland releases —> migrates to liver —> prod. of IGF —> bone muscle and skin
- too much as child = gigantism
- too much as adult = acromegaly - sharp features etc
lymphatic and immune system
- LYMPHATIC VESSELS - carry lymph fluid & lymphocytes from peripheral tissues to veins of CV sys (blood)
- LYMPHATIC FLUID - all extra fluid around cells + lipids from gut
- LYMPH NODES (incl. tonsils - back of throat) - monitor composition of lymph, engilf pathogens, immune response (B&T)
- SPLEEN - next to left side of stomach. immune resp, engulf pathogens, recycle RBC, monitors circulation blood cells
- THYMUS - development and maintenance of T cell lymphocytes
- lymph. sys. absorb excess interstitial fluid and transport (proteins and fluid) to CV sys
cardiovascular system
- HEART - maintains BP, propels blood
- BLOOD VESSELS - arteries = from heart to cap. cap = diffusion between blood and interstitial fliuds. veins = return blood from cap to heart
- BLOOD = transport of o2 ans co2, nutrients, hormones, removes waste, temp, acid base balance, defense against illness (immune cells)
respiratory system
- NASAL CAVITY & SINUSES - filter warm humidify air, smells
- PHARYNX - air to larynx
- LARYNX - protects opening to trachea, vocal chords
- TRACHEA - conducts air, cartilage keeps open
- BRONCHI - air from trach. to lungs
- LUNGS - air movement, gas exchange, acid base control
digestive system
- ORAL CAVITY - break up food w teeth tongue
- SALIVARY GLANDS - (acid base) buffer, lubricant, enzymes eg. amylase
- PHARYNX - solid and liquid to oes.
- OESOPHAGUS - food to stomach
- STOMACH - secrets acid enzymes hormones
- SMALL INTESTINE - digestive enzymes, buffers and hormones, absorbs nutrients
- LIVER - bile, reg. nutrients in blood
- GALLBLADDER - concentrates bile
- PANCREAS - dig. enzymes, buffers, endocrine cells
- LARGE INTESTINE & ANUS - water removal, waste storage & removal
urinary system
- KIDNEYS - form and concentrate urine, reg. pH and ions, blood vol and pressure
- URETERS - urine to bladder
- BLADDER - stores urine
- URETHRA - urine to exterior
EPO
- glycoprotein hormone produced by kidney
- signals for erythropoesis in bone marrow - production of RBC
- more hemocytoblasts (RBC stem cells) = RBC prod. —> blood carry more o2
reproductive system FEMALE
- OVARIES (gonad) - oocytes hormones
- UTERINE TUBES - delivery oocyte location of fertilisation
- UTERUS - embryonic development
- VAG & EXTERNAL GENITALS - lubrication, birth canal, sperm reception
- MAMMARY GLANDS - nutrition for newborn
reproductive system MALE
- TESTES (gonad) - hormones, sperm prod
- EPIDIDYMIS - s mature
- DUCTUS DEFERENS - s from epididi
- SEMINAL & PROSTATE GLANDS - seminal fluid
- URETHRA - s to exterior
- PENIS & SCROTUM - reprod. thermal, control testes
4 types of tissues are…
EPITHELIAL
CONNECTIVE
MUSCLE
NERVOUS
epithelial tissue
covers body surfaces
lines hollow organs tubes cavities ducts
forms glands
protection filtration secretion excretion absorption
connective tissue
cells in matrix of fibres and ground substance (inc. blood) - CT = ECM + cells
not on body surfaces, highly vascular (unlike epi. except cartilage avasc; tendons little blood supply), supplied by nerves (like epi. except cartilage)
protects, supports connects body organs
transport- distributes blood vessels to other tissues
stores energy (adipose tissue)
nervous tissue
conducting nerve cells and supportive neuroglia
detects changes and carries info through generating nerve impulses
5 typesof junctions are..
TIGHT ADHERENS DESMOSOMES HEMIDESMOSOMES GAP
tight junctions
strands of transmembrane proteins (claudin, occludin), more strands = tighter
prevent migration of proteins between apical & basal surfaces, prevent contents of organs leaking to blood
LOCATIONS - stomach, intestine, bladder
adherens junctions
belt desmosome/adhesion belt (plaque layer of proteins)
more basal than tj
cadherins spans gap - catenins link cadherin to actin (microfilament on plaque), crosses intercellular space & attaches to cadherin of adj. cell
prevent cell from separation during contraction
LOCATIONS - intestines,
desmosomes
plaque attaches to intermediate filaments - keratin
k spans from one side of desmosome to other - stability
cadherin link cell surface to keratin, span gap
resist shearing forces
LOCATIONS - cardiac muscle cells, epidermal cells, skin epithelium
hemidesmosomes
anchor epithelia to bm
plaque
INTEGRIN linker protein binds to LAMININ in bm and KERATIN in cytoplasm
gap junctions
direct connection between cells —> communication
6 connexINs —> 1 connexon / hemichannel —> 2 connexons = gap junction (hydrophillic channel)
ions, small mol. (~1kDa mol.) diff from one cystol to another. NOT large molecules eg. protein
LOCATIONS - mucles , nerves (impulses), heart, gastointestinal tract, uterus
cytoskeleton
MICROFILAMENTS (eg. actin) - bundles beneath cell mem. and cyt. , strength, alter cell shape, link cyt to mem, tie cells together, muscle contraction INTERMEDIATE FILAMENTS (eg keratin) - strength, move materials through cytoplasm