Cells and DNA Flashcards
BLENDING INHERITANCE
Darwin’s idea that offspring would be an “average” of their parents (not correct)
ISSUE WITH BLENDING INHERITANCE
- cannot explain how variation persists across generations
- dilutes and eventually eliminates variation
- traits would continuously blend and average out, eventually leading to a population with uniform characteristics, making natural selection impossible
THE CELL
Basic unit of life (comprised of genetic material)
PROKARYOTIC CELLS
Single-celled organisms without a nucleus.
EUKRAYOTIC CELLS
Complex cells with a nucleus and organelles.
CHROMOSONES
- Small linear bodies contained in every cell
- Replicated during cell division
- Exist in homologous pairs in diploid organisms
CELL DIVISON: MITOSIS
The division of cells in which two exact copies of chromosome pairs are made (diploid)
CELL DIVISON: MEIOSIS
Cell division creating haploid gametes for reproduction
FERTILIZATION
The process in which haploid sperm join haploid ovum to produce a zygote. (zygote is diploid)
DNA
- Double helix of nucleotides with phosphate-sugar backbone
- Stores information
- The chemical basis of hereditary
- Responsible for the genetic makeup of an individual
- Adenine (A) only bonds with Thymine (T)
- Cytosine (C) only bonds with Guanine (G)
- “Alphabet” with four repeating letters in infinite combinations
DIFFERENCES IN DNA SEQUENCE LEAD TO VARTIATION THROUGH TWO WAYS:
1) Some DNA codes for proteins
2) Some DNA codes for regulatory sequences
GENE
- Segment of DNA that makes a functional product
- Unit of hereditary, specifies traits
- Arranged on chromosomes “like beads on a string”
- Each gene found at a specific point on the chromosome (locus)
- Segregates as a unit during gamete formation
PROTEIN-CODING GENES
DNA sequences code for two main types of protein:
- Enzymes
- Non-enzymatic proteins
ENZYMES
Proteins that catalyze chemical reactions in cells
EXONS
- Coding sequences in genes, spliced together
- Covalently bonded to one another to create mature mRNA
INTRONS
- Non-coding sequences removed during RNA processing
- Intros are removed by RNA splicing as RNA matures, meaning that they are not expressed in the final messenger RNA (mRNA)
REGULATAORY SEQUNCES
DNA segments controlling gene expression timing
MUTATIONS
- Changes in DNA sequence
- Can cause a change in chromosome # / structure
- Not always negative, source of variation
POINT MUTATION
Change in a single DNA base
RECOMBINATIONS
- New combinations of alleles
- Created through the breaking and rejoining of DNA strands in a new order
- Source of variation
HOMOZYGOUS
The individual carries two identical alleles for a given gene
HETEROZYGOUS
The individual carries two different alleles for a given gene
DOMINANT TRAIT
An allele that suppresses other alleles
RECESSIVE TRAIT
An allele whose expression is suppressed by dominant forms
No effect on phenotypes in heterozygotes