CELLS Flashcards
(Bacterial vs Animal & Plant cell, Characteristics of Cells, Cell Cycle, Phagocytosis, Oncogenes, Stem Cells)
Basic unit of life
Cell
Characteristics of cells (there are 4)
- Surrounded by a plasma membrane
- Have a semi-fluid substance within the membrane called cytosol
- Contains chromosomes that have genes in the form of dna
- Have ribosomes, tiny organelles that make proteins using the instructions contained in genes
Series of growth and development steps a cell undergoes
Cell Cycle
Stages of cell cyle
- Interphase (G1, S, G2 phase), cell grows and makes a copy of its DNA
- Mitotic phase (cell division)
G1 - Cell grows
S (Synthesis) - synthesizes DNA
G2 - grows some more before dividing
Mitosis in animal cells
Prophase, prometaphase, metaphase, anaphase, telophase
Mitosis involves one division, diploid parent cell (2n), 2 diploid daughter cells identical to parent cells
Meiosis in animal cells
Prophase 1/2, metaphase 1/2, anaphase 1/2, telophase 1/2
Meiosis involves the production of gametes, 2 cell divisions, diploid parent cell, 4 haploid daughter cells, crossing over and synapsis offer variation
Cell cycle control/regulation
DNA is checked to make sure in has replicated correctly, chemical signals tell a cell when to start and stop dividing, neighboring cells communicate to regulate their growth
regulation checkpoints
G1, S (stops cell with damaged dna), M (stops cells when chromosomes are not attached to spindles)
programmed cell death
apoptosis
what happens to dead cells when scavenger cells (macrophages) engulf them
phagocytosis
Cells that do not follow signals in the cell cycle and divide excessively which invades other tissues
Cancer cells
cancer-causing genes
oncogenes
(onco = tumor)
normal versions of cellular genes
proto-oncogenes
Benign vs Malignant tumor
B: few genetic or cellular changes
M: genetic or cellular changes enough to spread to other tissues
These cells reproduce itself indefinitely and replenish their own population and generate new cells. It also differentiates into specialized cells
Stem cells of animals
Types of stem cells and describe
- Embryonic stem cell - pluripotent (all cell types)
- Adult stem cell - multipotent (not all cell types)
- Induced pluripotent stem cells (iPS) - AS -> ES
Applications of stem cells
- supply cells for repair of damaged organs (bone marrow transplants)
Cloning of embryos for medical application
stem cell therapy