Cell Wall Synthesis Inhibitors (cephalosporins) Flashcards
0
Q
2nd generation
- cefotetan
- cefoxitin
- cefuroxime
- cefaclor
A
Less gram(+) activity and more gram(-) activity than 1st gen.
- B.fragilis
- H.influenziae
- M.catarrhalis
- P.mirabilis
- E.coli
- K.pneumoniae
- Neisseria
- Enterobacter
1
Q
1st generation
Cefazolin
Cephalexin
A
Gram(+)
Proteus mirabilis
E.coli
K.pneumoniae
2
Q
3rd generation
- ceftazidime
- cefoperazone
- cefotaxime
- ceftriaxone
A
Less gram(+) and more gram(-) activity than 2nd gen.
- Serratia sp.
- B.burdorferis
- H.influenzae
- Neisseria
- Enterobacter
- Some anti-pseudomonas activity
3
Q
4th generation
-cefepime
A
More gram negative activity than 3rd and same gram positive as 1st
