Cell's Potency Flashcards
Types of cells potency
Pluripotent, Oligopotent, Totipotent, Unipotent, Multipotent
3 cell types
Stem, progenitor, precursor cell [SPP]
Types of stem cells
[EAFA] Embryonic, Adult, Fetal, Amniotic stem cells
Differentiates to all types of cells
Totipotent
Differentiates in any 3 germ layers, and most of the cells except placental tissues
Pluripotent
Differentiates into a range of cells within the tissue
Multipotent
Differentiates only into 1 cell type
Unipotent (___blast–>___cytes)
Lymphoid/myeloid stem cells develop into…
B and T cells
Develop into few cell types
Oligopotent progenitor cells
Vascular stem cells develop into…
Endothelial and smooth muscle cells
Type of cell that divides only a limites num of times, found in most adults and acts as a repair system
Progenitor
What triggers progenitor cells to start differentiating into target cells
Growth factors or cytokines
Type of cell in the “center” between stem cells and fullt differentiated cells
Progenitor
Type of cell aka blast cell/blast, a partially differentiated cell
Precursor
Alternative term for unipotent stem cells
Precursor cells
Group of cells that differentiates later into 1 organ, and only 1 cell type; aka intermediate cell before differentiated
Precursor
Can differentiate into other types
Stem cell
Type of cell that can divide in self-renewal to produce more
Stem
2 broad types of stem cells, and the rest
Embryonic and adult stem cell, fetal and amniotic
Type of stem cell that xan differentiate into 3 germ cells n also maintains normal turnover lf regenerative organs
Embryonic
Found in various tissues of fully developed mammals; both this and progenitor cells act as repair system
Adult stem
3 accessible sources of autologous adult stem cells
Bone marrow, Adipose Tissue, blood
Can be taken from umbilical cord blood after birth (type of stem cell)
Adult
2 properties of stem cells
Self renewal and potency
Wats self renewal
Ability 2 go thru multiple cycles of cell division while remaining undifferentiated
2 mechanisms of self renewal and define
Asymmetric cell division - divides into differentiated and undiff stem cell; Stochastic (stalk astic) differentiation - ganern
Primitive sten cells in fetuses
Fetus stem cells
2 types of fetal stem cells n define
Fetal proper - obtained after ablrtion, multipotent; extraembryonic fetal - from extraembryonic membranes, after birth, and pluripotent
Aka somatic stem cell, and its two types
Adult; lineage restrkcting (multipotemt)and muse (pluripotent) (multiliniage stress endurinv cell)
Multipotent stem cells in amniotic fluid; very active, not tumorgenic
Amniotic stem cell
(ESC) Blastocyst stage is reached ____ days after fertilization which consists of ____ cells
4-5 days; 50-150 cells
Type of stem cell thats pluripotent and can differentiate to 200 types of cell
Esc