Cell proliferation Flashcards
1
Q
What is aneuploidy?
A
The occurrence of one or more extra or missing chromosomes in a cell or organism.
2
Q
What is polyploidy?
A
Inheritable condition of possessing more than two complete sets of chromosomes.
3
Q
What are cyclins?
A
Are stress-sensitive proteins.
Bind to, and activate, kinases.
4
Q
Which stage of meiosis are female oocytes arrested in until their first menstrual cycle?
A
Prophase 1
5
Q
What stage of meiosis are secondary female oocytes arrested in before being fertilised?
A
Metaphase 2
6
Q
What is a checkpoint in the cell cycle?
A
Can halt cell cycle and promote cell death in some circumstances.
This protects the organism from DNA damage or replication failure.
7
Q
What can occur due to checkpoint defects?
A
polyploidy or aneuploidy.
