Cell potential and self-renewal Flashcards

1
Q

What is cell potency

A

the range of commitment options available to a cell

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2
Q

Name the three compounds that make up the blastocyst

A

trophectoderm, epiblast, primitive endoderm

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3
Q

describe the stages from a zygote to blastocyst

A

fusion of gametes to form zygote, cleavage of cells to form blastomeres, more cleavage to form morula, Cells on the outside form trophectoderm layer and inside form inner cell mass and segregate into epiblast and primitive endoderm

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4
Q

which potency can produce a fully functional organism

A

totipotent

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5
Q

which potency can only differentiate into one cell type

A

unipotent

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6
Q

which potency can produce all body’s cell lineage, including germ cells and all extraembryonic cell types

A

pluripotent

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7
Q

which potency can form mulitple lineages that constitute an entire tissue

A

multipotent

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8
Q

which potency can differentiate into all three germ layers

A

pluripotent

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9
Q

which is the potency of most adult stem cells

A

mulitpotent

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10
Q

potency of spermatogonial sc

A

unipotent

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11
Q

how to show a cell is multipotent

A

inject a single cell and show it can make all blood lineages

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12
Q

how to show a cell is multipotent and can self-renew

A

do a secondary single cell transplant to prove the first cell injected can make perfect copies of itself and also can make all blood lineages

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