Cell Membrane Transport Flashcards
Cell membranes are ___ b/c the phospholipids move around and behaved like a liquid, and ___ b/c there are numerous different types of proteins and carbs. associated with it
fluid; mosaic
Phospholipids have a ___ head and a ___ tail
hydrophilic; hydrophobic
The membrane is ___
nonpolar
Anything that is ___ will NOT cross the membrane very easily b/c they are large
polar
Transport across membrane that does NOT require energy; high to low concentration
EX. punch a hole in a bag of sand and the sand will leave b/c there is more on the inside than the outside
passive
transport across membrane that DOES require energy; low to high concentration
EX. if you have 10 glucose molecules on the inside of the cell and 3 on the outside, glucose will move OUT of the cell passively, w/o energy, but glucose will only move into the cell if energy is used
active
Areas with more molecules (solute) are areas of high __ and high energy
concentration
Difference in charge b/w inside and outside of cell
EX. -70 mV inside = 70 mV more negative than the outside
membrane potential
There is ALWAYS more __+ outside the cell that inside
Na+
There is ALWAYS more __+ inside the cell than outside
K+
Charged molecules can’t cross w/o help of other ___ b/c ions have a charge and membrane itself does NOT
proteins
Measure of the factors that determined which direction ions move across membrane
driving force
___ force is a concentration gradient
chemical
In chemical force, there is always more potassium (K+) inside the cell than outside, so the chemical force wants to move K+ ___ of the cell
outside
In chemical force, there is always more sodium (Na+) outside of the cell than inside, so the chemical force always wants to push Na+ ___ of the cell
inside
No matter what, the chemical driving force never ___
changes
Since Na+ and K+ are both positive ions, each will be attracted to ___-___ areas and be repelled by ___-____ areas
**like charges repel, and opposite charges attract
negatively-charged; positively-charged
If the membrane potential is negative, the electrical driving force will try to bring ___ and ___ into cell
Na+; K+
If membrane potential is positive, the electrical driving force will try to push ___ and ___ out of the cell
Na+; K+
Resting membrane potential for most cells
-70 mV
Sum total of the chemical and electrical force acting on an ion
electrochemical driving force
When electrical force is now larger than the chemical force
equilibrium potential
Equilibrium potential for Na+ is +55 mV. Na+ will go into the cell most of the time, but for Na+ to leave the cell, the inside would have to be really ___, more than +55 mV
positive
Equilibrium potential for K+ is -94 mV. K+ will leave the cell. For K+ to enter the cell, the inside of the cell must be really ___, more ___ than -94 mV
negative
The membrane potential, at ANY time, will always be approaching equilibrium potential of the MOST permeable ___
ion
Membrane potential tells use that at rest, the membrane potential is -70mV. What does this tell us?
that there is more K+ leaving the cell at rest than there is Na+ entering