Cell Membrane Flashcards
also called plasma membrane is a biological membrane separating the interior of a cell from the outside environment.
Cell membrane
regulates the flow of materials into and out of cell-selectively permeable. Selective Permeability - it allows some substances to cross it more easily than others.
Function of cell membrane
Four major classes are commonly present in cell membrane.
Phospholipids (most abundant), spingolipids, glycolipids, and sterols (e.g., cholesterol). All of them are amphipathic
Lipids
Contains hydrophobic tails buried in the interior of the membrane and the hydrophilic head groups exposed on both sides, in contact with water. (Most abundant)
High concentration of cholesterol may increase the rigidity and decrease the flexibility of the membrane, affecting membrane protein movement and function.
Phospholipid
Cell membrane contains about 50% of this
Protein
Permanently attached to cell membrane
Embedded in the whole membrane
Contain both hydrophobic and hydrophilic parts
Integral (intrinsic) protein
Temporarily attached to cell membrane
Loosely bound to the surface of the membrane
Contain hydrophilic parts
Peripheral (extrinsic) protein
present in exterior or polar end of phospholipids at the external surface of plasma membrane.
Carbohydrates
developed by cell biologists, Seymour Jonathan Singer and Garth L. Nicolson in 1972
describes the structure of the plasma membrane as a mosaic of components - including phospholipids, cholesterol, proteins, and carbohydrates that gives the membrane a fluid character.
Fluid mosaic model