Cell Mediated Immune Responsee Flashcards
Where are lymphocytes made, where do the diff types mature
Bone marrow
B lymphocytes mature in the bone marrow
T lymphocytes mature in the thymus
What are antigen presenting cells
Phagocytes that engulf the virus present some of the pathogens antigens on their own cell membrane
Why are there different types of t lymphocytes
Each T cell has a specific receptor on its cell membrane
What are the stages of the cell mediated response
- pathogen invades and is destroyed by phagocytosis
- phagocyte becomes apc
- receptors from t lymphocytes bind to specific antigen
- t helper cell is activated
- t helper cell divides rapidly by mitosis forming clones
What are the 4 things that the cloned t helper cells do
1: develop into memory cells enabling a rapid response next infection
2: stimulate phagocytes to engulf more pathogens
3: stimulate b lymphocytes to divide and secrete more antibodies
4: activate cytotoxic T cells
What are cytotoxic T cells and what do they do
Cytotoxic T cells produce a protein called perforin which makes holes in the cell membrane of target cells, this causes the cell to become freely permeable to substances and ultimately die