Cell Mediated Immune Responsee Flashcards

1
Q

Where are lymphocytes made, where do the diff types mature

A

Bone marrow
B lymphocytes mature in the bone marrow
T lymphocytes mature in the thymus

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2
Q

What are antigen presenting cells

A

Phagocytes that engulf the virus present some of the pathogens antigens on their own cell membrane

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3
Q

Why are there different types of t lymphocytes

A

Each T cell has a specific receptor on its cell membrane

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4
Q

What are the stages of the cell mediated response

A
  • pathogen invades and is destroyed by phagocytosis
  • phagocyte becomes apc
  • receptors from t lymphocytes bind to specific antigen
  • t helper cell is activated
  • t helper cell divides rapidly by mitosis forming clones
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5
Q

What are the 4 things that the cloned t helper cells do

A

1: develop into memory cells enabling a rapid response next infection
2: stimulate phagocytes to engulf more pathogens
3: stimulate b lymphocytes to divide and secrete more antibodies
4: activate cytotoxic T cells

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6
Q

What are cytotoxic T cells and what do they do

A

Cytotoxic T cells produce a protein called perforin which makes holes in the cell membrane of target cells, this causes the cell to become freely permeable to substances and ultimately die

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