Antigens And Phagocytosis Flashcards
What are antigens
A protein with a specific shape that triggers an immune response from a lymphocyte, chemical markers on the surface of cells
What antigens does your body recognise
Self antigens
What are non self antigens and what happens when its in ur body
Different antigens that are recognised as foreign and will be attacked in an immune response
What 4 things to antigens allow the immune system to identify
Pathogens
Cells from other organisms of the same species, like transplanted organs
Abnormal body cells
Toxins
What are phagocytes
White blood cells made in the bone marrow
How do phagocytes travel
They travel in capillaries but have adapted to change shape and squeeze through walls into tissues
What are the two types of phagocytes
Neutrophils
Macrophages
What do neutrophills do
Engulf and digest pathogens and dead human cells/debris
What do macrophages do
Can become antigen presenting cells to stimulate the specific immune response
What is phagocytosis
Cellular proscess of engulfing solid particles using the cell membrane and carried out by phagocytes
What are the steps of phagocytosis
- chemotaxis
-attaches
-engulfed
-lysosomes
-release
-exocytosis
-pathogen produces chemicals which attracts a phagocyte, known as chemotaxis
-pathogen is recognised as having non self antigens and attaches to the phagocyte by cell surface receptors
-pathogen is engulfed by phagocyte by endocytosis forming a phagosome
-lysosomes fuse to phagosome to form a phagolysosome and release h2o2,Hcl and digestive enzymes into phagosome to digest pathogen
- harmless products are removed by exocytosis or used by phagocyte