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Molecular Cell Biology > Cell joining > Flashcards

Cell joining Flashcards

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AP® Biology flashcards Biology 101 flashcards
1
Q

Types of Tissue

A

Connective, Muscle tissue, epithelial tissue and nervous tissue

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2
Q

Types of adhesion

A

Cell-cell and cell to matrix

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3
Q

How does Cell to cell adhesion work

A

Uses Cell Adhesion molecules

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4
Q

How does cell to matrix adhesion work

A

Occurs through adhesion receptors to the ECM

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5
Q

What are the different junctions

A

Gap, Adheren, Desmosomes, and tight

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6
Q

Role of tight junctions

A

Hold tissue together

Control solute flow and allow polarisation of the plasma membrane

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7
Q

Role of Gap junctions

A

Allow diffusion, help communication

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8
Q

Role of Adheren Junctions

A

Hold tissue together

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9
Q

Role of Desmosomes

A

Hold tissue together

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10
Q

What are the anchoring junctions

A

Desmosomes and Adherens

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11
Q

What are the anchoring junctions

A

Desmosomes and Adherens

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12
Q

What are integral proteins

A

Inside the cells

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13
Q

Integral proteins for Tight junctions

A

Occludin and Claudin

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14
Q

What are JAMS

A

Type of CAm junction adhesion molecule

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15
Q

What are adherens made of

A

5 e-cadherins joined both cis and trans with Ca2+ inbetween them. linked to actin cytoskeletin via intracellular adapters

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16
Q

Adheren intracellular adapters

A

b- catenin, a-catenin, f-actin, vinculin, p120-catenin

17
Q

What are desmosomes made of

A

cadherins. cytoplamic plaque linked to intermediate filaments

18
Q

What are the cadherins for desmosomes

A

Desmoglein and desmocollin

19
Q

What are in the cytoplamis plaque

A

plakoglobin, desmoplakins and plakophillins

20
Q

Gap junctions components

A

Have 2 connexons, innexins and pannexins allow for diect cytoplamic transfer of molecules

21
Q

What are connexins

A

They consist of a hemichannel with 6 connexin molecules

22
Q

Cell-ECM

A

Focal adhesion and Hemidesmosomes

23
Q

What are hemidesmosomes

A

Link cells to ECM, integrins link cytosolic intermediate filaments to the basal lamina via laminin. Epithilial

24
Q

Hemidesmosomes integral proteins

A

example plakins

25
Q

Integrins for Hemidesmosomes

A

alpha and Beta

26
Q

Focal Adhesion

A

cells to ECM for example muscle cell to tendon. Via fibronectin in non-epithelial tissues.

27
Q

How does Integrin bind in Focal adhesion

A

Binds to the fibronectin via RGD motif

28
Q

What is RGD

A

Arg, Gly, Asp

Molecular Cell Biology (3 decks)

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