Cell IV: Lysosomal Storage diseases Flashcards
1
Q
Glycogenosis
A
Type II Pompe’s
2
Q
Sphingolipidosis
A
GM1 gangliosidosis GM2 gangliosidosis (Tay Sachs) GM2 gangliosidosis (Sandoff)
3
Q
Sulfatidosis
A
Metachromatic leukodystrophy
Gaucher
4
Q
Mucopolysaccharidosis
A
Hurler
5
Q
Type II Pompe Disease
A
- glycogenosis
- alpha-1,4,-glucosidase deficiency
- accumulates glycogen
6
Q
GM1 gangliosidosis
A
- sphingolipidosis
- GM1 ganglioside B galactosidase
- GM1 ganglioside, galactose containing oligosaccharides
7
Q
GM2 gangliosidosis Tay Sachs
A
- sphingolipidosis
- Hexosaminidase alpha subunit
- GM2 ganglioside
8
Q
GM2 gangliosidosis Sandoff
A
- sphingolipidosis
- Hexosaminidase B subunit
- GM2 ganglioside, globoside
9
Q
Metachromatic Leukodystrophy
A
- sulfatidosis
- Arylsulfatase A
- Sulfatide
10
Q
Gaucher
A
- sulfatidosis
- Glucocerebrosidase
- Glucocerebroside
11
Q
Hurler
A
- mucopolysaccharidosis
- alpha-L-Iduronidase
- Dermatan sulfate, heparan sulfate
