Cell Intro Flashcards

1
Q

What did Matthias Schleiden and Theodor Schwann do

A
  • determined that cells are the universal building blocks of all living tissue
  • this led to modern cell theory
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2
Q

how dod Schleiden and Schwann come to their discoveries

A

through examination of plant and animal tissues

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3
Q

what are the elements of cell theory

A
  • cells are the basic unit of life
  • all living organisms are composed of one or more cells
  • new cells are generated only from preexisting cells
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4
Q

do cells look different based on their function

A

yes

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5
Q

what have prokaryotic cells

A
  • bacteria
  • archaea
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6
Q

what have eukaryotic cells

A
  • plant
  • animal
  • fungi
  • protists and other complex unicellular organisms
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7
Q

describe the differences in nuclei between prokaryotes and eukaryotes

A
  • prokaryote absent
  • eukaryote present
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8
Q

describe the differences in cell size between prokaryotes and eukaryotes

A
  • prokaryote 1um
  • eukaryote 10-100um
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9
Q

describe the differences in structure between prokaryotes and eukaryotes

A
  • prokaryote unicellular
  • eukaryote mostly multicellular, some unicellular
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10
Q

describe the differences in cytoskeleton between prokaryotes and eukaryotes

A
  • prokaryote simple
  • eukaryote complex
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11
Q

describe the differences in membrane-bound organelles between prokaryotes and eukaryotes

A
  • prokaryote absent
  • eukaryote present
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12
Q

describe the differences in DNA content between prokaryotes and eukaryotes

A
  • prokaryote 1-5 million base pairs
  • eukaryote 15 million to 5 billion base pairs
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13
Q

describe the differences in chromosomes between prokaryotes and eukaryotes

A
  • prokaryote circular, single
  • eukaryote linear, multiple
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14
Q

where is DNA found in prokaryotic cells

A
  • no nucleus present
  • found in distinct areas
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15
Q

where are ribosomes found in prokaryotic cells

A

free in cytoplasm

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16
Q

describe the envelope of a prokaryotic cell

A
  • inner plasma membrane
  • peptidoglycan cell wall
  • lipopolysaccharide outer membrane (in some cases)
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17
Q

describe a key feature of dictyostelium discoideum

A
  • unicellular
  • when nutrients are scarce, they turn into a multicellular “slug” to go look for food
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18
Q

describe the internal membranes of eukaryotic cells

A
  • lots of membranes (both internal and external)
  • internal membranes organize and create intracellular compartments w diff functions
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19
Q

describe the plasma membrane role

A
  • selective barrier that separated a cell form its surroundings
  • composed of a phospholipid bilayer embedded w proteins and sometimes carbohydrates
  • facilitates intra and extracellular communication through budding and fusing of vesicles in the processes of endo and exocytosis
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20
Q

describe the nucleus

A
  • contains most of the DNA of the cell
  • prominent nucleoli may be visible
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21
Q

what encloses the nucleus

A
  • 2 concentric membranes that form the nuclear envelope
  • perforated by nuclear pores
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22
Q

what happens when DNA and protein combine

A

forms chromatin

23
Q

describe the mitochondria

A
  • harnesses energy from food molecules to produce ATP
24
Q

what encloses the mitochondria

A
  • 2 membranes: smooth outer and highly convoluted inner
25
describe DNA in mitochondria
- mitochondria have their own DNA - reproduce by dividing
26
describe chloroplasts
- large, green organelles found in plants and lagae - capture energy from sunlight
27
what encloses chloroplasts
- 2 membranes - also possess internal stacks of membranes containing chlorophyll
28
describe DNA in chloroplasts
- contain their own DNA - reproduce by dividing
29
describe endoplasmic reticulum
- irregular maze of interconnected spaces enclosed within a membrane that is continuous with the nuclear envelope - involved in the production of many cell components
30
describe rough ER
- studded with ribosomes - translate RNA into protein
31
describe smooth ER
- no ribosomes - involved in the synthesis/ storage of lipids
32
what is the golgi apparatus
- comprised of stacks of flattened membrane-enclosed sacs - typically located near the nucleus - modified and packages molecules made in the ER that are to be secreted or transported to another cell compartment
33
what is the cytosol
- part of the cytoplasm not containing within intracellular membranes - very crowded with molecules
34
how does the cytosol behave
like a water-based gel
35
what is the difference between cytoplasm and cytosol
- **cytoplasm** everything in the cell - **cytosol** the "empty space" around the other organelles
36
what does the cytoskeleton do
- governs internal organization - strength - shape - movement
37
what is the cytoskeleton made up of
protein filaments (anchored across the cell)
38
what are the primary kinds of cytoskeleton
- **actin filaments** muscle contraction - **microtubules** helps during cell division - **intermediate** cell structure and strength
39
what came first: RNA or DNA
RNA
40
if RNA came first, what are two things that RNA must be able to do
- store genetic info - facilitate its own replication via catalytic properties
41
what about the central dogma confused researchers, and what was the solution
- AA were needed to form proteins, but proteins were needed to form AA - one needed to be there before the other in order to create the other - **solution** must have been autocatalytic
42
what does autocatalytic mean
feeds into itself
43
describe the RNA world hypothesis as it evolved to where we are now
- initially autocatalytic RNA only forming itself - RNA then begins to direct protein synthesis - DNA then takes over as genetic material, RNA becomes an intermediate between DNA and protein
44
what is the endosymbiont theory
- explains the origin of eukaryotic cells - eukaryotes might have originated as a predator that ate other cells - suggests that mitochondria and chloroplasts were eaten by a eukaryote and thats how they become special organelles
45
what characteristics of mitochondria support the endosymbiont theory
- own DNA (circular) - double membranes - self-replicating
46
what are used too study life's common heritage and how
- genomic comparisons - can use this info to relate one biological system to another
47
what are some key features of a model system
- reproduce rapidly - convenient for genetic manipulation - easy to handle in a lab setting
48
why do we use e. coli as a model organism
- understand the working more thoroughly than any other living organism - lives in the gut of humans and other vertebrates, but also grows happily and rapidly in a culture bottle - we've learnt a lot about genes and DNA from them
49
why do we use yeast as a model system
- is a simple eukaryote (we are eukaryotes too) - easy and cheap to keep and reprodues rapidly - reproduces almost as rapidly as bacteria, but is a eukaryote - taught us a lot about cell division
50
why do we use arabidopsis as a model system
- can be grown indoors in large numbers - one plant can produce thousands of offspring in 8-10 weeks - taught us a lot about the physiology of crop plants that our lives depend on
51
why do we study caenorhabditis elegans as a model system
- a worm that attacks roots of crops - develops with clockwork precision, and always has exactly 959 body cells - has an incredibly precise minute by minute understanding of how they develop
52
why do we study drosophila melanogaster as a model system
- shows us how genetic instructions in DNA direct zygote development - d. melanogaster mutants with odd patterns or limbs give the key to identifying genes that are needed for a proper body - these genes are very similar to those of humans
53
why do we study d rerio as a model system
- they are transparent for the first two weeks of their life - provides an idea system to observe how cells behave during development in a living animal
54
what is another name for d rerio
zebrafish