Cell Injury and Death Flashcards
Caseous necrosis
crumbly and yellow resembling cheese (quesidilla) – TB
Fat necrosis
dead fat, flecks of yellow, gritty material – Pancreatitis
Coagulative necrosis
retains normal tissue appearance other than color – usually indicates sudden loss of local blood supply
Liquefactive necrosis
Not just dead, but liquefied – tissue is liquefied by enzymes from white cells (granulocytes)
Gangrene
necrosis usually applied to necrotic limbs or digits – Common to DM
Molecules released into the blood from injured or killed liver cells
Transaminase
Creatine phosphokinase (CPK)
converts creatine to phosphocreatine, a source of stored chemical energy in skeletal muscle.
release of intracellular proteins from dead skeletal muscle cells
CPK, myoglobin
Primary positive ion in Plasma and Interstitial fluid
Na+
Primary positive ion in intracellular fluid
K+
Ca++ concentration is much higher in the _____cellular space
extracellular
megakaryocytes are precursors to______
platelets
Why is splenomegaly associated with Malaria?
Malaria shortens life of RBC and they accumulate in the spleen
myocardial infarction releases which proteins in the blood stream?
troponins
liver cells release which proteins upon cell death?
aminotransferases
