Cell Form and Function Flashcards
Blood cells
no nucleus, donut shaped
allows to fit in tiny spaces and carry oxygen
liver cells
hepatocytes. Lots of RER
protein synth
muscles cells
long fibers. actin and myosin
neruons
long cells. lots of vessicles (esp at end of neuron)
mircovilli
inc SA for absorption
in GI tract
cytoskeleton
cell skeleton. hold organelles in position maintain cell shape hold cell in shape changes in it used to change cell shape moves organelles
cell adhesion/junctions
ways cells connect to each other
ECM
excreted by cells
support and stability
communication
Epidermis
epidermal layer- carotinocytes
basal lamina- cell junctions that connect epidermis to underlying CT
dermis: CT. composed mostly of ECM, low cell density
Cytoskeleton made of:
microtubules: made of tubulin
intermediate filaments: carotin proteins
microfilaments: actin and its interaction with motor unit myosin
microtubules
largest
alpha and beta subunits. form tubulin dimer
all eukaryotes have them
long and strait
microfilaments
smallest actin monomer polymerized (subunits) all eukaryotes have them often just under cell membrane supports cell membrane traffics molecules around cell membrane shorter, more branched
intermediate filaments
fibrous filaments (subunits) strung together in cords
mostly just animal cells, not plant cells
composed of different intermediate filament proteins
Just mechanical strength (no movement)
over 100 kinds
microtubule movement
cilia: small one. multiple cilia to move substances across organism membrane. Moves food
flagella: large one. 1 or 2 to move organism. Moves self
Both: center at some point
transport material around cells
ALSO: pull apart in cell division
Cell Crawling
Microfilaments
Actin process
Microfilaments spread out, pushes membrane out, form lamellipodium (LEADING EDGE)
Trailing edge, drags behind
Direction depends on receptors, signals it receives
Actin fibers push out lamellapodium, trailing end contracts behind
how WBC find things to kill
free living cells finding nutrients
Microfilaments found…
in epithelial cells in small intestine
microvilli: actin extensions and binding proteins
microfilaments
muscle contraction
move things in cells
final separation of daughercells
ALL ACtiN RELATED PROCESSES
lamins
intermediate filaments that support nucleus
carotins
intermediate filaments at epithelial cells
intermediate filaments attached at
desmosomes
rivets that hold cells together
attachment of intermediaterofilaments
Defects in intermediate filaments: Epidermolysis Bullosa
Genetic defect in intermediate fillaments
adjacent cells very lose, light contact disrupts cells, skin flakes off
Test for Cancer Spread
intermediate filaments from cancerous cells in places where they don’t belong
indicates that cell type is moving around body when it shouldnt
look at lymphatic system
indication of matastises
Mircrotubules and Microfilaments
always changing
polarity:
Plus side: End that most rapidly polymerizes
Negative side: slower polymerization
can polymerized and depolymerize at BOTH ends
polymerization
growing