Cell Division: Mitosis and Meiosis Flashcards
_______________ is based on cell division or the reproduction of cells.
The continuity of life
It is an ordered series of events involving cell growth.
Cell cycle
Cell division produces _____ new daughter cells.
Two (2)
What is the first step in the cell cycle?
Interphase: G1 phase (First Gap, or Gap 1)
Explain what occurs in Gap 1 phase
The cell increases in size and volumes, and carbohydrates, lipids, proteins, and enzymes, are produced in preparation for S & M phase.
G1 phase occurs in the first ___ hours of the cell cycle.
Ten (10)
Cell division, or mitosis, occurs in what kind of cell?
Somatic cells
What is the next step after G1?
G1/S Checkpoint
What occurs during the G1/S checkpoint?
Damages in DNA are checked, and if the cell does not meet the checkpoint requirements, it will go back to a resting phase called G0.
Stimulating proteins include?
Growth factors, Cyclin and Cyclin Dependent Kinases
Inhibiting proteins include?
TP53 protein, Retinoblastoma (Rb) protein
What does TP53 protein do?
It is a tumor suppressor. Used to regulate and control the production of tumors (that occurs in the cell cycle).
What does retinoblastoma protein do?
It is also a tumor suppressor protein
This is also called resting phase, or non-dividing phase, where the cells fail from the G1/S checkpoint.
G0 phase
Cells are (allowed or not allowed?) to go back to the cell cycle if they are in the G0 phase.
Allowed, provided that they have the sufficient resources to grow and divide.
Why do cells go into G0 phase instead of proceeding to S phase?
It receives a signal to differentiate, or when resources (such as nutrients and DNA) are insufficient to grow and divide.
S phase stands for?
Synthesis
Explain what happens during S phase
From the word “SYNTHESIS” itself, this phase synthesizes DNA to prepare for cell division. By the end of the S phase, there will be 2 complete sets of chromosomes.
How long does the S phase last?
8 hours
What organelle is produced in S phase?
Centrosomes
What are centrosomes?
They are a small organelle found in eukaryotic cells that functions as a microtubule organization center.
What happens during G2 phase?
The cell increases in size and volume, replenishes its energy, and tubulin dimers are synthesized. These occur to prepare the cell for M phase (Mitosis).
_______ ensures that all DNA are completely and correctly replicated.
G2 (G/M) phase.
If the cell fails in G2 (G/M) Checkpoint, where does it go?
G0 phase, again