Cell Cycle & Apoptosis

Question 0

give four reasons why a cell might commit apoptosis.

Answer 0

excessive DNA damage
infected by viruses
cancer
metamorphosis.

Question 1

what is required for cells to exit mitosis!

Answer 1

cycling B degradation.

Question 2

What three steps occur after the formation of an embryo?

Answer 2

cleavage, blastula, gastrula.

Question 3

how was it discovered that Pax6 was vital to eye formation?

Answer 3

ECTOPIC eyes induced in drosophila (on legs).

Question 4

briefly outline the extrinsic and intrinsic apoptotic pathways.

Answer 4

extrinsic - extracellular signals bind CSDRs –> caspase activation.
intrinsic - cytochrome c release from mitochondria –> cytosol.m

Question 5

what is a blastula?

Answer 5

a hollowed embryo.

Question 6

what is the order of events after sperm penetration?

Answer 6

cortical reaction
egg activation (2nd meiotic division)
male/female pronuclear fusion.

Question 7

what is the order of phases of the cell cycle?

Answer 7

G1
S
G2
M