Cell Cycle Flashcards

1
Q

What does cell division result in?

A

identical daughter cells (most cell division)

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2
Q

WHat is a genome?

A

all the DNA in a cell (total genetic info)

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3
Q

What are DNA molecules packed into?

A

Chromosomes

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4
Q

What are somatic cells?

A

non reproductive cells with 2 sets of chromosomes

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5
Q

What are Gametes?

A

reproductive cells (sperm and eggs) that have half as many chromosomes as somatic cells

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6
Q

What are sister chromatids?

A

duplicated chromosomes with replicated DNA

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7
Q

What is the centromere?

A

narrow waist where the two chromatids are closely attached

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8
Q

What are the two cell cycle phases?

A

Mitotic phase and interphase

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9
Q

how is interphase split up?

A
G1 phase (Cell growth and organelle duplication
S phase (DNA synthesis, Chromosome duplication)
G2 phase ( cell growth preparing for mitosis
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10
Q

What phases is mitosis split into?

A

Prophase, prometaphase, metaphase, anaphase, and telophase

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11
Q

what is the mitotic spindle?

A

microtubules controlling chromosome movement during mitosis. includes centrosomes, spindle microtubules, and the asters

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12
Q

CEntrosome:

A

microtubule organizing center

one centrosome at each end of cell with microtubules growing out of them

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13
Q

Aster?

A

radial array of short microtubules extending from each centrosome

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14
Q

Spindle microtubules

A

kinetochore- Bind to sister chromatids

non kinetochore. unbinded, elongate with tubulin subunits to hold shape of cell

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15
Q

G2 interphase

A

nuclear envelope intact, nucleoli present

centrosome duplicates, chromatin duplicate

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16
Q

Prophase

A

nucleoili disappear, chromatin fibers tighten to form chromosomes.
centrosomes move away from eachother as microtubules lengthen
mitotic spindle forms

17
Q

prometaphase

A

nuclear envelope disintegrates; chromosomes condensed even more
microtubules attach to kinetochores on chromosomes

18
Q

metaphase

A

centrosomes at opposite ends of cell

chromosomes settle at metaphase plate

19
Q

Anaphase

A

separase enzyme cleaves cohesion protens to allow chromatids to separate
chromatids move to poles of cell as kinetochore microtubules shorten by depolymerization
non-kinetochore microtubules lenthen and push against eachother to elongate cell

20
Q

Telophase

A

daughter cells divide along cleavage furrow as two new nuclei form

21
Q

What is binary fission?

A

asexual reproduction of prokaryotes (bacteria and archaea)

22
Q

What is the cell cycle control system?

A

Where the events of the cell cycle are directed.
It has check points at the G1 phase, G2 phase and Mitotic phase. each phase must meet requirements to continue to the next phase

23
Q

what are the two types of regulatory proteins in cell cycle?

A

Cyclins and cyclin-dependant kinases (Cdks)

24
Q

what is MPF (maturation-promoting factor)

A

cyclin-Cdk complex that triggers a cells passage past G2 checkpoint to Mitotic phase

25
what are examples of external signals of cell division?
Density-dependent inhibition- crowded cells stop dividing Anchorage dependence- cells must be attatched to a substratum for division Cancer cells exhibit neither of these
26
what are benign and malignant tumors?
benign is when abnormal cells remains at the origional site | Malignant tumors invade surrounding tissues and can metastasize, exporting cancer cells to other part of the body