Cell Cycle Flashcards
What does cell division result in?
identical daughter cells (most cell division)
WHat is a genome?
all the DNA in a cell (total genetic info)
What are DNA molecules packed into?
Chromosomes
What are somatic cells?
non reproductive cells with 2 sets of chromosomes
What are Gametes?
reproductive cells (sperm and eggs) that have half as many chromosomes as somatic cells
What are sister chromatids?
duplicated chromosomes with replicated DNA
What is the centromere?
narrow waist where the two chromatids are closely attached
What are the two cell cycle phases?
Mitotic phase and interphase
how is interphase split up?
G1 phase (Cell growth and organelle duplication S phase (DNA synthesis, Chromosome duplication) G2 phase ( cell growth preparing for mitosis
What phases is mitosis split into?
Prophase, prometaphase, metaphase, anaphase, and telophase
what is the mitotic spindle?
microtubules controlling chromosome movement during mitosis. includes centrosomes, spindle microtubules, and the asters
CEntrosome:
microtubule organizing center
one centrosome at each end of cell with microtubules growing out of them
Aster?
radial array of short microtubules extending from each centrosome
Spindle microtubules
kinetochore- Bind to sister chromatids
non kinetochore. unbinded, elongate with tubulin subunits to hold shape of cell
G2 interphase
nuclear envelope intact, nucleoli present
centrosome duplicates, chromatin duplicate
Prophase
nucleoili disappear, chromatin fibers tighten to form chromosomes.
centrosomes move away from eachother as microtubules lengthen
mitotic spindle forms
prometaphase
nuclear envelope disintegrates; chromosomes condensed even more
microtubules attach to kinetochores on chromosomes
metaphase
centrosomes at opposite ends of cell
chromosomes settle at metaphase plate
Anaphase
separase enzyme cleaves cohesion protens to allow chromatids to separate
chromatids move to poles of cell as kinetochore microtubules shorten by depolymerization
non-kinetochore microtubules lenthen and push against eachother to elongate cell
Telophase
daughter cells divide along cleavage furrow as two new nuclei form
What is binary fission?
asexual reproduction of prokaryotes (bacteria and archaea)
What is the cell cycle control system?
Where the events of the cell cycle are directed.
It has check points at the G1 phase, G2 phase and Mitotic phase. each phase must meet requirements to continue to the next phase
what are the two types of regulatory proteins in cell cycle?
Cyclins and cyclin-dependant kinases (Cdks)
what is MPF (maturation-promoting factor)
cyclin-Cdk complex that triggers a cells passage past G2 checkpoint to Mitotic phase