cell cycle Flashcards

1
Q
  • longest event in the cycle
  • has three (3) substages: G1, S, and G2 phases
  • length of the cycle is approximately 24 hours
A

interphase

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2
Q
  • sequence of events where duplication of organelles and preparation for cell division occur
  • cell grows and makes a new copy of DNA
  • packs enough nutrients for the new daughter cells
A

interphase

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3
Q
  • first checkpoint and called as the restriction point
  • cell grows larger and duplicates the organelles
  • makes the molecular building blocks needed for the succeeding steps
  • cells will take between 5-6 hours to complete S phase
A

First Gap (G1)

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4
Q
  • DNA replication and duplication of centrosomes occurs
  • requires 10–12 hours
  • occupies about half of the cell cycle
A

Synthesis Phase (S)

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5
Q
  • continuation of G1 and the second checkpoint
  • cell grows continuously
  • fills up the loss of energy during the S phase
A

Second Gap (G2)

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6
Q
  • making more proteins
  • continuously duplicating the organelles
  • completing the preparations for the mitotic phase
  • lasting only 4-6 hours
A

Second Gap (G2)

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7
Q
  • last checkpoint
  • involves two distinct division-related processes: mitosis and cytokinesis
  • lasting only >1 hour
A

Mitotic Phase (M)

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8
Q

Mitotic Phase (M)

  • distribution of chromosomes into two daughter nuclei
  • takes place in four stages: PMAT
A

mitosis or karyokinesis

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9
Q

Mitotic Phase (M)

division of the cytoplasm producing two daughter cells

A

cytokinesis

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10
Q

Duration of the Cell Cycle

24 hours

A

whole cell cycle

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11
Q

Duration of the Cell Cycle

5 to 6 hours

A

G1 Phase

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12
Q

Duration of the Cell Cycle

10 to 12 hours

A

S Phase

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13
Q

Duration of the Cell Cycle

4 to 6 hours

A

G2 Phase

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14
Q

Duration of the Cell Cycle

> 1 hour

A

M Phase

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15
Q

What would happen if the size is too small or if it has reserve enough only for
itself?

A

Gap 0 Phase (G0)

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16
Q

What happens to the two daughter cells produced in one round of the cell cycle?

A

Gap 1 Phase (G1)

17
Q

Why do cells enter G0 phase?

A
  • unfavorable environmental conditions
  • permanent state for some cells like nerve and cardiac muscle cells
  • waiting for signals to enter G1 (don’t divide but performs function)
18
Q
  • also known as the resting phase
  • non-dividing and maintains itself
A

Gap 0 Phase (G0)

19
Q

Substages of the Interphase

metabolic activity and growth

A

G1 Phase

20
Q

Substages of the Interphase

metabolic activity, growth, and DNA synthesis

A

S Phase

21
Q

Substages of the Interphase

metabolic activity, growth, and preparation for cell division

A

G2 Phase

22
Q

Control System

Who are responsible in these checkpoints?

A

control system of the cell cycle (includes the cyclins, the cyclin-dependent kinases and p53)

23
Q

Control System

undergo a constant cycle of synthesis and degradation during cell division

A

cyclin

24
Q

Control System

an activating protein that binds to a kinase to form CDK complex

A

cyclin

25
Q

Control System

activates or deactivates another protein by phosphorylating them

A

CDK complexes

26
Q

Control System

gives the ‘stop’ and ‘go’ signal at the Gap 1 and Gap 2 checkpoints

A

CDK complexes

27
Q

Control System

a cyclin-CDK complex that triggers a cell’s passage past the G2 checkpoint into the M phase

A

MPF (maturation-promoting factor)

28
Q

Control System

  • “guardian of the genome”
  • prevents gene mutation
A

p53

29
Q

Control System

two types of regulatory proteins involved in cell cycle control:

A

Cyclins & Cyclin-dependent Kinases (CDK)

30
Q

Control System

responsible for suppressing tumors, repairs the damaged DNA, and trigger apoptosis if the damaged is beyond repair

A

p53

31
Q

is the process of programmed cell death and is used during early development to eliminate unwanted cells

A

apoptosis