Cell 2 To 5 Flashcards
Organelles affected in cell injury
Mito
Endoplasmic reticulum
Nucleus
Plasma membrane
Most common feature of cell injury
Cellular swelling
Irreversible cell injury mito damage characteristics
1 EM
2 light micro
1 large flocculant amorphus densities
2 nuclear changes
Different process of cell death
Necrosis Apoptosis Pyroptosis Necroptosis Ferroptosis Autophagy
Necrosis process and types
Denaturation of protein and enzymatic digestion of cells Coagulative Liquefactive Caseous Fat Fibrinoid Gangrenous
Apoptosis earliest feature and charcteristics feature
E : cell shrinkage
C: chromatin condensation
Connective tissue metaplasia?
Myositis ossificans
Free radicals damage to cells
Protein misfolding
DNA damage
Lipid membrane damage
Brain is protected by free radical ?
And mutation of that may lead to
SOD1 superoxide dimustase
Mutation can lead to amyotrophic lateral sclerosis
Coagulative necrosis seen in which organs
Heart mc, spleen, kidney
Liquefactive necrosis seen in
Brain , abscesses, fungal infection
Caseous necrosis seen in
TB , fungal
In severe diabetic nephropathy lesion ?
Armani epstein lesions
Hyaline accumulation in alcoholic liver diseases
Mallory hyaline
Endogenous pigments
Lipofuscin
Hemosiderin
Melanin
