CELECOXIB Flashcards
What type of receptor does celecoxib primarily inhibit?
Celecoxib primarily inhibits the COX-2 receptor.
True or False: Celecoxib is a non-selective COX inhibitor.
False: Celecoxib is a selective COX-2 inhibitor.
What is the primary action of celecoxib?
The primary action of celecoxib is to reduce inflammation and pain.
Fill in the blank: Celecoxib is commonly used to treat __________.
arthritis and acute pain.
What are common adverse effects of celecoxib?
Common adverse effects include gastrointestinal issues, cardiovascular risks, and skin reactions.
Multiple choice: Which of the following is a serious adverse effect of celecoxib? A) Nausea B) Heart attack C) Headache
B) Heart attack
What physiological effects does celecoxib have on the body?
Celecoxib reduces pain and inflammation by inhibiting prostaglandin synthesis.
True or False: Celecoxib has a lower risk of gastrointestinal bleeding compared to non-selective NSAIDs.
True
What drug interactions should be considered when prescribing celecoxib?
Celecoxib may interact with anticoagulants, other NSAIDs, and certain antihypertensives.
Fill in the blank: Celecoxib should be used with caution in patients with __________.
cardiovascular disease.
What is the mechanism by which celecoxib reduces inflammation?
Celecoxib reduces inflammation by selectively inhibiting COX-2, leading to decreased prostaglandin production.
Multiple choice: Which condition is NOT typically treated with celecoxib? A) Osteoarthritis B) Rheumatoid arthritis C) Diabetes
C) Diabetes
What is the significance of COX-2 selectivity in celecoxib?
COX-2 selectivity aims to minimize gastrointestinal side effects associated with COX-1 inhibition.
True or False: Celecoxib is safe for long-term use in all patients.
False: Long-term use may increase cardiovascular and renal risks.
What should be monitored in patients taking celecoxib long-term?
Patients should be monitored for cardiovascular health and renal function.
Fill in the blank: Celecoxib is contraindicated in patients with a history of __________.
sulfa allergy.
What is the primary route of elimination for celecoxib?
Celecoxib is primarily eliminated through hepatic metabolism.
Multiple choice: Celecoxib is classified under which category of drugs? A) Opioids B) NSAIDs C) Antibiotics
B) NSAIDs
What is a key consideration when prescribing celecoxib to elderly patients?
Elderly patients may have an increased risk of adverse cardiovascular effects.
True or False: Celecoxib can be taken with food to reduce gastrointestinal discomfort.
True
