C.diff Flashcards
1
Q
Symptoms
A
Diarrhoea
2
Q
Who is most at risk?
A
Elderly
Middle aged women
3
Q
Common causing antibiotics
A
- Clindamycin
- Cephalosporins (esp 3rd + 4th gen)
- Fluoroquinolones
- Broad spectrum e.g. co-amoxiclav
4
Q
Factors that increase infection risk
A
Longer duration of abx treatment.
Concurrent use of multiple antibacterials
Multiple courses
PPIs
65+
Prolonged hospitalisation
5
Q
First episode of mild, moderate, or severe C. difficile infection
A
1st = Vancomycin 125 mg QDS for 10 days
2nd = Fidoxamicin 200 mg BD for 10 days
5
Q
Further episode - within 12 weeks
A
- Fidoxamicin
6
Q
Further episode - after 12 weeks
A
Vancomycin or Fidoxamicin
7
Q
Life-threatening C.diff
A
Vancomycin 500 mg QDS AND Metronidazole 500 mg IV TDS for 10 days
8
Q
Loperamide
A
Contraindicated
