CDI

Question 1

Non-severe CDI

Answer 1

TW < 15 and SCr <133
PO Vancomycin 125 mg QDS x 10-14 days or
PO Metronidazole 400 mg TDS x 10-14 days

Question 2

Severe CDI

Answer 2

WBC >15 OR SCr >133
PO Vancomycin 125 mg QDS x 10-14 days

Question 3

Fulminant CDI

Answer 3

Iles or hypotension
IV Metronidazole 500 mg q8 hours +
PO Vancomycin 500 mg QDS +/-
PR Vancomycin 500 mg QDS x 10-14 days

Question 4

First recurrence of CDI, previously Vancomycin used

Answer 4

PO Vancomycin 125 mg QDS x 10-14 days –> 125 mg BD x 7 days –> 125 mg OD x 7 days –> 125 mg q2-3 days x 2-8 weeks

Question 5

First recurrence of CDI, previously Metronidazole used

Answer 5

PO Vancomycin 125 mg QDS x 10 days