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TCR signaling > CD molecules > Flashcards

CD molecules Flashcards

1
Q

CD71

A

TNFR1 associates with zap70 and lat in the 1st 5 in of TCR isignaling (mallisen)

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2
Q

CD229

A

SLAMF3: Associates with both zap70 and lat

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3
Q

CD6

A

surface receptor that assocates with SLP76 after TCR signaling (10s) and Zap70
CD6 (but not LAT) is required for SLP76 recruitment and phosphorylation follow CD3 CD4 stimulation

Ligand: CD166 ALCAM

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4
Q

CD6 binding partners

A

Vav-1, SLP76 and zap70

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5
Q

CD6-SLP76 interaction

A

SH2 domain of SLP76 directly associates with pY662 of CD6 cytoplasmic motife

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6
Q

CD166

A

ALCAM, A ligand for CD6

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TCR signaling (5 decks)

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