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Skin MS: Week 3 > CD, Eczema, SD > Flashcards

CD, Eczema, SD Flashcards

1
Q

Types of Dermatitis

A

Atopic Dermatitis (Eczema)
Contact Dermatitis
Seborrheic Dermatitis
Photodermatitis

(Stasis dermatitis, multifactoral)

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2
Q

Chronic inflammatory skin condition characterized by pruritis, erythematous and scaly lesions often localized to flexural surfaces and may be associated w/ personal/family hx of atopic disease (asthma, allergic rhinitis)

A

Atopic Dermatitis

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3
Q

Genetic defect in ______ disrupting epidermis in Atopic dermatitis –> immune cells/antigens communicating

A

Filaggrin

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4
Q

Hallmark: Itching, tx w/ topical glucocorticoids Rx

A

Atopic dermatitis

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5
Q

Clinical features of atopic dermatitis

A

Pruritis
Facial/extensor papulovesicles in infancy
Flexural lichenification in adults and older children
Chronic-relapsing course
personal or family hx of atopic dz

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6
Q

Differential Dx for AD

A

Congenital, chronic dermatoses, infection/infestation, malignancies, immunodeficiencies, metabolic disorders, immunologic disorders

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7
Q

Tx for AD

A

Cutaneous hydration-emollients
Topical Glucocorticoids Rx
Identify and eliminate flare factors
Tx of pruritis (antihistamines, tar)

Second line -
protopic, topical immunomodulator inhibits Tcell activation
Eliden - calcineurin inhibitor

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8
Q

Complications of AD

A

eye, infections, hand dermatitis, exfoliative dermatitis, impetigo, herpes inf, contact sensitization

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9
Q

Prognosis for AD

A

spontaneous resolution after age 5 in 40%, 84% outgrow by adolescence

worse if more sxs of atopy

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10
Q

Hallmark: Linear, some itching too

A

Contact Dermatitis

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11
Q

Inflammatory reaction of skin precipitated by exogenous chemical

A

Contact dermatitis

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12
Q

Two types of CD

A

Irritant - direct toxic effect

Allergic - immunologic rexn that causes tissue inflammation (Type IV hypersensitivity)

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13
Q

Clinical features of acute vs. chronic

A

Acute - linear streaks of vesicles (poison ivy especially)

Chronic - lichenification, eczematous rexn

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14
Q

Differential for CD

A

Atopic dermatitis, seborrheic dermatitis, stasis dermatitis, fungal infec, bacterial cellulitis

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15
Q

Lab testing for CD

A

No testing for irritant

Patch testing for allergic CD

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16
Q

CD tx

A

Prevention-Allergen avoidance
Symptomatic tx
physiochemical barriers
tolerance induction

17
Q

Chronic, superficial inflammatory process affecting hairy regions of body (scalp, eyebrows and face especially)

A

Seborrheic dermatitis

18
Q

One of the most common skin manifestations in patients with HIV, paralysis/quadriplegia, parkinsons

A

Seborrheic dermatitis

19
Q

Two peaks of SD

A

Infancy in first 3 mo, adult 40-70

20
Q

Clinical Features of SD

A 
Bilateral, symmetrical
Predilection for hairy regions
Patches and plaques w/ indistinct margins
Dandruff
Uncommon to have hair loss
21
Q

Differential Dx of SD

A

Atopic dermatitis, psoriasis, tinea capitis, SLE, rosacea, histiocytosis X

22
Q

Drugs causing SD rash

A

Arsenic, gold, methyldopa, cimetidine, neuroleptics

23
Q

Physical factors for SD

A 
Seasonal variation (worse in autumn, winter) 
Those who get PUVA for psoriasis at risk (mask face)
24
Q

Tx goals for SD

A 
Loosening and removal of scales and crusts
Inhibition of yeast colonization
Control of secondary inf
Reduction of erythema and itching
Control rathe than cure
25
Q

Tx of SD for infants (cradle cap)

A

Removal of crusts with 3-5% salicylic acid in olive oil or water soluble base
Warm olive oil compresses
low potency glucocorticoids
mild baby shampoos
Drying lotions in skin folds, tx for candidiasis

26
Q

Tx of SD for adults

A

Anti-inflammatory, antifungal, kerolytics

daily shampoo w/ special ingredients
crusts - can remove overnight w/ topical glucocorticoids or salicylic acid in water soluble base
Tinctures/alcohol AGGRAVATE

Antifungals (imidazoles, metronidazole)

27
Q

Immune based dermatitis in which UV light alters antigen to make it an effective immunogen resulting in typer IV cell mediated reactions

A

Photodermatitis

28
Q

Commonly seen with _____ and _______ - Photodermatitis

A

thiazide diuretics and tetracyclines

29
Q

Tx photodermatitis

A

stop med, UVA/UVB blocker sunscreen

Skin MS: Week 3 (14 decks)

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