CBG 25 Flashcards
why study immunology?
control infectious diesease
understand and treat cancer/autoimmune diseases/allergy
transplants- blood/liver/kidney
veterinary immunology-economic lifestock
top 5 infectious diseases that kill? (5)
how many deaths in millions in 2001 according to WHO?
respiratory infections e.g RSV 3.8
HIV-AIDs 2.8
diarrheal diseases 2
tuberculosis 1.6
malaria 1.1
WHAT 4 THINGS AFFECT THE IMMUNE SYSTEM? what are their sizes?
1) viruses 20-40nm
2) fungi 1-5um
3) bacteria (varies)
4) parasites(vary e.g metazoan worms 3mm-7mm)
what properties to cbacterial and viral have that means the immune system has to constantly suppress them?
they grow exponentially, they evolve rapidly and adapt
What are some main innate immunity responses?
1) epithelial barriers
2) phagocytes
3) complement
4) NK cells
what are some properties of innate responses?
rapid,fixed,limited specificity, constant ,0-12 hrs
What are some properties of an adaptive response?
slow,variable,numerous highly selective specificities,improves during response, 0-5days etc
are B and T-lymphocytes part of the innate response?
NO they are part of the adaptive response
what are antibodies and effectors part of?
adaptive response
what things are part of the adaptive response and what are part of the innate?(4 each)
Innate
1) NK cells
2) complement
3) epithelial cells (skin barrier)
4) phagocytes
Adaptive
1) t lymphocytes
2) b lymphocytes
3) antibodies
4) effectors
are b and t cells specific receptors based on present events?
no they are past on past events
what is blood serum?
cell free liquid
No clotting factors
what is plasma?
cell free liquid WITH clotting factors
what are the plasma components? what %?
water 92%
proteins 7%
other solutes 1% (e.g electrolytes)
what three things is blood composed of?
1) plasma
2) erythocytes-red blood cells
3) Buffy coat- platelets and leukocytes
where do all stems come from? where?
hematopletic stem cell in bone marrow
where do cells become t cells?
thymus