CBD AML Flashcards

1
Q

3 gejala leukimia akut

A
  1. kegagalan sumsum tulang
  2. hiperkatabolik
  3. infiltrasi ke dalam organ
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2
Q

gejala kegagalan sumsum tulang

A

anemia : pucat dan lemah
neutropenia : infeksi (demam, infeksi saluran napas, infeksi kulit, syok, syok sepsis)
trombositopenia (perdarahan gusi dan epistaksis)

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3
Q

gejala hiperkatabolik

A
  1. kaheksia
  2. keringat malam
  3. hiperurikemia (gout dan gagal ginjal)
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4
Q

infiltrasi ke dalam organ

A
  1. nyeri tulang
  2. limfadenopati superfisial
  3. splenomegaly
  4. hepatomegaly
  5. hipertrofi gusi
  6. infiltrasi kulit
  7. sindrom meningeal (sakit kepala, mual muntah, mata kabur, kaku kuduk)
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5
Q

aml vs all apusan darah tepi

A

aml : batang auer, penurunan jumlah granulosit absolut
all : peningkatan leukosit, limfositosis, penurunan jumlah trombosit, neutrofil, eritrosit

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6
Q

aml vs all morfologi

A

aml : kromatin lebih halus, nukleoli lebih prominen, lebih banyak (>2), auer rod (+), sel pengiring neutrofil
all : kromatin lebih bergumpal, nukleoli lebih samar, lebih sedikit, auer rod (-), sel pengiring limfosit

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7
Q

aml vs all (sitokimia)

A

aml : mielopreoksidase (+), sudan black (+), esterase non spesifik (+), periodic acid schiff (+) monositik, acid phosfatase (+) halus, platelet peroxidase (+) M7
all : periodic acid schiff kasar, acid phosfatase (+) Thy ALL

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8
Q

aml vs all enzim

A

aml : serum lysozime (+) monositik
all : terminal deoxynucleotydyl transferase (+)

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