CBC and anemia Flashcards

1
Q

Female Hgb

A

12-14 g/dL

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

male hgb

A

14-16 g/dL

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

female Hct %

A

36-43

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

male Hct %

A

42-48%

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Hgb g to %

A

10 g = 30%
12 g = 36%
15g = 45%

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

MCV microcytic

A

small cell, MCV < 80 fL

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

MCV macrocytic

A

abnormally large cell, MCV > 100 fL

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Normocytic:

A

normal cell, MCV 80-100 fL

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

MCH ~

MCHC ~

A

Mean Cell Hemoglobin

Mean Cell Hemoglobin Concentration

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Vitamin B12~Pernicious Anemia ~ Folate-Deficiency

A

macrocytic, normochromic w/high MCV

Abnormally large RBC d/t altered RNA:DNA ratio, hgb usually normal; new RBC larger than old ones  elevated RDW Usu. Hgb, hct, rbc – all slightly low; mcv usu elevated, rdw – elevated

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Hypochromic:

A

pale, MCHC=<31 g/dL

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What is the rdw?

A

Red Blood Cell Distribution Width
Index of variation in RBC size
Normal = 11.5%-15%

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

RDW >15%,

A

indicating that new cells differ in size (smaller or larger) compared with older cells

This is one of the earliest laboratory indicators of an evolving microcytic or macrocytic anemia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

what are steps for diagnosing anemia

A

Review current laboratory results looking at Hgb/Hct first

  1. IF there is an abnormal level, HOW abnormal is it?
  2. NEXT, review trends over time . . .
  3. THEN, look at the MCV .
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

what are steps for diagnosing anemia

A

Review current laboratory results looking at Hgb/Hct first

  1. IF there is an abnormal level, HOW abnormal is it?
  2. NEXT, review trends over time . . .
  3. THEN, look at the MCV .
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Low values of MCV indicate the cells are microcytic (small cells) and are often evident with conditions such as ?

A

iron deficiency, lead poisoning and the thalassemia’s

17
Q

MCV High values greater than 100 fL indicate macrocytic cells (large cells), and are found with such conditions as?

A

megaloblastic anemia, folate or Vitamin B12 deficiency, liver disease, post-splenectomy, chemotherapy or hypothyroidism.

18
Q
  1. normocytic, normochromic w/normal MCV
  2. microcytic, hypochromic w/low MCV, high RDW
  3. microcytic, hypochromic w/low MCV, normal RDW
  4. macrocytic, normochromic high MCV but not pernicious anemia
A
  1. hgb=10.1, hct=32%, MCV=82  most common etiology is acute blood loss or anemia of chronic disease (RDW, MCV - WNL) (usually low RBC)
  2. Hgb=10.3, hct=30%, MCV=70  most common etiology is Iron-deficiency anemia (and increased RDW d/t # small, new cells w/old ones); low RBC.
  3. Hgb=11.6, hct=36.7, MCV=69, RDW –normal (11.5-15%)  most common etiology thalassemia
  4. Hgb=10.2, hct=32, MCV=120, RDW=18% (high).  most common etiology is vitamin B12, pernicious anemia, folate-deficiency anemia; and if high MCV w/out anemia – drugs/etoh
19
Q
  1. normocytic, normochromic w/normal MCV
  2. microcytic, hypochromic w/low MCV, high RDW
  3. microcytic, hypochromic w/low MCV, normal RDW
  4. macrocytic, normochromic high MCV but not pernicious anemia
A
  1. hgb=10.1, hct=32%, MCV=82  most common etiology is acute blood loss or anemia of chronic disease (RDW, MCV - WNL) (usually low RBC)
  2. Hgb=10.3, hct=30%, MCV=70  most common etiology is Iron-deficiency anemia (and increased RDW d/t # small, new cells w/old ones); low RBC.
  3. Hgb=11.6, hct=36.7, MCV=69, RDW –normal (11.5-15%)  most common etiology thalassemia
  4. Hgb=10.2, hct=32, MCV=120, RDW=18% (high).  most common etiology is vitamin B12, pernicious anemia, folate-deficiency anemia; and if high MCV w/out anemia – drugs/etoh
20
Q

What is stocking and Glove neuropathy?

A

Symptoms
Stocking and glove neuropathy presents as the sensation of tightness, pins and needles, or tingling in the areas where an individual would wear a pair of gloves or stockings. Some patients suffer pain in addition to the stocking and glove sensation. The condition usually begins as loss of feeling and a tingling sensation and gradually worsens if left untreated.

21
Q

What causes stocking and glove neuropathy

A

Causes
The most common causes of stocking and glove neuropathy include type 1 and type 2 diabetes, AIDS, alcohol abuse, use of certain drugs, old age, and exposure to environmental toxins. Less common causes include trauma and genetic disposition. In approximately one-third of the cases of stocking and glove neuropathy, no evidence of a specific cause exists.