CBC Flashcards

1
Q

What is in a CBC? (9 items)

A

WBC, RBC, Hgb, Hct, MCV, MCH, MCHC, RDW, Plt

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2
Q

WBC norm value?

A

4-10,000/mm3

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3
Q

RBC norm value?

A

3.5-5.0 mil/mm3

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4
Q

Hgb norm value?

A

12-17 grams%

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5
Q

Hct norm percentage?

A

36-52%

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6
Q

MCV norm value?

A

82-94 fl

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7
Q

MCH norm value?

A

27-31 pg

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8
Q

MCHC norm percentage?

A

32-35%

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9
Q

RDW norm percentage?

A

10-12.5 %

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10
Q

Plt. norm value?

A

150,000-400,000 /mm3

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11
Q

What can increased RBC levels indicate?

A

dehydration or bone marrow disorders like polycythemia vera

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12
Q

What does RDW stand for?

A

Red cell distribution width

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13
Q

What happens to RDW’s in anemia?

A

They increase

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14
Q

RBC variation should be within what percentage?

A

11.5% - 15%

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15
Q

A high RDW test means what?

A

the red blood cells measured varied widely in size.

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16
Q

Abnormal RDW (red cell distribution width) can be associated with what pathologies?

A

anemias, liver disease and a deficiency in folate.

17
Q

RBC elevated over the norm of 3.5-5.0 million/ mm3 can indicate?

A

Dehydration due to less vascular volume or bone marrow disorders like polycythemia vera which is an overproduction of RBC’s.

18
Q

RBC numbers lower than 3.5 million /mm3 can be an indicator of?

A

anemias, RBC hemolysis and hemoglobinopathies.

19
Q

How do we diagnose anemias?

A

We use a CBC combined with Fe studies to diagnose anemias.

20
Q

What is the normal Hgb/Hct ratio?

A

1:3 for example 10g = 30%, 12 g = 36%, 15g = 45%

21
Q

How do you measure RBC size?

A

Wintrobes classification of anemia by evaluation of mean corpuscle volume or MCV.

22
Q

RBC that are microcytic are?

A

A small cell with MCV <80fL

23
Q

RBC’s that are normocytic are?

A

A normal size with MCV 80-96fL

24
Q

RBC’s that are macrocytic are?

A

A large size with MCV>96fL

25
Q

How do we measure the RBC hemoglobin content?

A

By evaluating the MCH (Mean corpuscular hemoglobin) and the MCHC (Mean cell hemoglobin concentration) (measuring the color and amount of heme

26
Q

What is the source of RBC color?

A

Hemoglobin (another word for color is “chromic”)

27
Q

Normochromic RBC measurements read as?

A

MCHC 31-37g/dl

28
Q

Hypochromic RBC measurements read as?

A

Pale, MCHC <31g/dl