CAW Basics Flashcards
3 types of mesh
Synthetic, Biologics, Bioresorbable
Biological Mesh Response in Body
Cells penetrate implant pores Enzymatic Degradation Angiogenesis Cells and collagen proliferate Natural tissue completely replaces graph
Wound Healing Race
Winning: wound heals before graft remodels
Not winning: graft degrades before wound heals
Why wouldn’t a surgeon want to use a synthetic graft?
Infection or contamination, synthetic mesh is permanent
Why use a biologic?
Graft goes away, less foreign body response
What is XenMatrix mesh madeout of
non-cross linked porcine dermis
XenMatrix’s open _______ strucure allows for early remodeling
collagen
Two antibiotics on Xenmatrix AB
Rifampin and Monocylin
Which two bacteria is XenMatrix known to protect against?
MRSA and E.Coli
How long does XenMatrix antibacterial coating last?
7-14 days
Polymer that binds antibacterial coating to Xenmatrix?
Tyrosine
Rifampin
kills bacteria
Minocyclin
stops replication of bacteria
Zone of Inhibition
We have a larger zone of inhibition than our competitors
Zone of inhibition is where the mesh is capable of inhibiting bacteria colonization
Repair strength of XenMatrix AB is ____ times stronger than the natural abdominal wall
3