Categories Flashcards
1
Q
Direct Agonists
A
Bethanechol
Carbachol
Methacholine
Pilocarpine
2
Q
Indirect Agonists (Anticholinesterases)
A
Galantamine donepezil rivastigmine Edrophonium Neostigmine Physostigmine Pyridostigmine
3
Q
Cholinesterase Inhibitor Poisoning
A
Often due to organophosphates, such as
parathion, that irreversibly inhibit AChE.
Causes:
Diarrhea Urination Miosis, Bronchospasm Bradycardia, Excitation of skeletal muscle and CNS Lacrimation Sweating, and Salivation.
May lead to
respiratory failure if untreated.
Antidote—atropine (competitive inhibitor) +
pralidoxime (regenerates AChE if given early).
