Cataracts - A Practitioner's Perspective Flashcards
What is a cataract?
opacity of the lens
What are the first questions to ask upon suspicion of a cataract?
- is it a cataract?
- what is the cause?
- are there other conditions present? If so, how can i be sure? How do I find out?
How do you find a cataract?
- examine the eye for opacities (cataracts): the position, presence & size
- use a mydriatic to examine (especially at the equatorial area)
What type of cataracts are usually stationary?
- nuclear
- capsular
Which cataracts are likely to progress?
- equatorial
- cortex
nuclear sclerosis starts around what age?
6-8 years old
Where within the eye do cataracts form?
on the lens at the centre of rotation posterior to the nucleus
What is the general composition of a cataract?
35% protein (85% soluble, 15% insoluble)
65% water
Composition of cataracts varies by…
species, location in the lens, age, and disease
the % soluble protein lowers with
age & is less in the cataractous lens
Cataract formation
- lens protein breaks into polypeptides & amino acids
- these diffuse thru the lens capsule into the anterior & posterior chamber
- molecules are not recognised by the immune system so trigger an immune response
- aka ‘lens-induced uveitis’
Nuclear sclerosis
at the lens equator, new lens cells are produced pushing older cells towards the nucleus & become tightly packed w/ reduced soluble fibre
What condition?
Nuclear sclerosis
What condition?
Nuclear sclerosis
At what age does nuclear sclerosis occur in dogs?
6-8 yrs old
At what age does nuclear sclerosis occurs in cats?
commences at ~12 yrs old
Explain the appearance of the nuclear sclerosis
- retina is visible thru the opacity
- on distant direct ophthalmoscopy - see a refractive ring in the middle of the lens
What is important to note about nucelar sclerosis compared to a cataract?
in nuclear sclerosis, vision is minimally affected until later on in the dz process
What are lens suture line opacities and when do they occur?
seen when the pupil is dilated in a young pup under 9 months old
Present at the tips of the anterior & posterior sutures
What condition?
lens suture line opacities
how are cataracts classified?
stage of dvlpmt
position w/i the lens
age of dvlpmt
cause
consistency
What are the stages of development of a cataract?
- incipient
- immature
- mature
- hypermature
- morgagnian
What are the signs of an incipient cataract?
- early focal opacity w/ the sight unaffected
- Freq. areas of dvlpmt: equatorial cortex, posterior subcapsular polar cotex, Y sutures, posterior cortical cataract
What stage of cataract development is present here?
incipient stage