Cases in general internal medicine 2 Flashcards

1
Q

At what level of Hb would you probably see SoB at

Why might you have a raised JVP in COPD

A

Below 80

Because of right heart failure secondary to pulmonary hypertension secondary to COPD

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2
Q

Onset of breathlessness; seconds

A
  • Pneumothorax
  • PE
  • FB (foreign body! Don’t forget this one)
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3
Q

Onset of breathlessness; mins/hrs

A
  • Airways (inflammation/obstruction)
  • Chest infection (pus)
  • Acute heart failure (fluid)
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4
Q

Onset of breathlessness; days/weeks

A

These(chronic/not resolving):

  • Airways (inflammation/obstruction)
  • Chest infection (pus)
  • Acute heart failure (fluid)

AND:

  • Interstitial lung disease
  • Malignancy/ Large pleural effusion
  • Neuromuscular
  • Anaemia/ Thyrotoxicosis
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5
Q

What is a primary pneumothorax

A

A primary spontaneous pneumothorax is one that occurs without an apparent cause and in the absence of significant lung disease

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6
Q

What is the management of primary pneumothorax

A

< 2 cm:
– Discharge, repeat CXR

> 2 cm OR THEY HAVE SOB:
– Aspiration
– If unsuccessful: chest drain

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7
Q

What is management of secondary pneumothorax

A

< 2 cm:
– Aspiration

> 2 cm:
– Chest drain

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8
Q

What could cause breathlessness after a chest drain insertion

A

Re-expansion pulmonary oedema

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9
Q

What is are lung bullae

A

A bulla is a permanent, air-filled space within the lung parenchyma that is at least 1 cm in size and has a thin or poorly defined wall;

NOT to be confused with pneumothorax!

You wouldn’t put a chest drain in for bullae.

Aka vanishing lung disease

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10
Q

When can it be called asbestosis

A

You can only call it asbestosis when there is pulmonary fibrosis

Asbestos lung disease gives you plaques, but this is not asbestosis

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11
Q

What are the types of opacity on xray and what are their respective DDx

A
  • Interstitial/alveolar shadowing (=fluid, pus, blood)
  • Reticulo‐nodular shadowing (fibrosis)
  • Homogeneous shadowing (pleural effusion)
  • Masses/cavitations
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12
Q

If a patient has a PE what drug do you think about in the first instance

A

LMWH (e.g. dalteparin)

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13
Q

If the x ray is very white, what can you say about penetration

A

Too white= underpenetrated

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14
Q

Should you be able to see the left hemidiaphragm behind the heart?

A

Yes you should! If you can’t, there’s something going on (e..g tumour or consolidation)

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15
Q

Air fluid level on X-ray/CT and reduced BS, hyper-resonant percussion notes

A

Bullous disease. Do not put drain in

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16
Q

……….

A

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17
Q

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A

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18
Q

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19
Q

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20
Q

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21
Q

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22
Q

ABDO…..

A

……..

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23
Q

Causes of hepatomegaly

A
• Cancer (primary or secondary deposits)
• Cirrhosis (early, usually alcoholic)
• Cardiac:
– Congestive cardiac failure
– Constrictive pericarditis

Infiltration

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24
Q

Give examples of infiltration causing hepatomegaly

A

Fatty infiltration, haemochromatosis, amyloidosis,

sarcoidosis, lymphoproliferative diseases

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25
Q

Causes of liver disease

A
Alcohol
• Autoimmune
• Drugs
• Viral
• Biliary disease
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26
Q

Causes of splenomegaly

A

H (portal Hypertension)
H (Haematological)
Infection
Inflammation

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27
Q
  • 75 year old man
  • Epigastric pain
  • Back pain
  • PR: 130 bpm
  • BP: 80/50 mm Hg

Likely diagnosis?

A. Peptic ulcer
B. Pancreatitis
C. Gastritis
D. GORD
E. Ruptured aortic aneurysm
A

E. Ruptured aortic aneurysm

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28
Q

Endo causes of acute abdominal pain

A

DKA

Addison’s

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29
Q

Epigastric pain DDx

A

Peptic ulcer
Gastritis
GORD
Malignancy

Acute pancreatitis
MI

ALSO:

• Above (heart)
– MI
• Below (Aorta)
– ruptured aortic aneurysm
• Right: (liver/gall bladder)
– Cholecystitis
– Hepatitis
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30
Q

What things point to acute pancreatitis

A
  • Pain

* High amylase

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31
Q

What is the test for chronic pancreatitis

A
Normal amylase
Faecal elastase (so need a stool sample)
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32
Q

What things point toward chronic pancreatitis

A

Pain, wt loss
• Loss of exocrine function
• Loss of endocrine function

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33
Q

5 causes RUQ

A

Gall bladder:
– Cholecystitis
– Cholangitis
– Gallstones

Liver:
• Hepatitis
• Abscess

Above (lungs)
– Basal pneumonia
Below (appendix)
– Appendicitis
Left (Stomach, pancreas)
– Peptic ulcer, Pancreatitis
Right: (kidney)
– pyelonephritis
34
Q

When ballotting the kidney you need to put your hand right under the back and press on the right upper quadrant

A

…..

35
Q

RIF pain

A
GI
– Appendicitis
– Mesenteric adenitis
– Colitis (IBD)
– Malignancy

Gynae
– Ovarian cyst rupture, twist, bleed
– Ectopic pregnancy

36
Q

Suprapubic pain

A
  • Cystitis

* Urinary retention

37
Q

LIF pain

A

GI
Diverticulitis
Colitis (IBD)
Malignancy

Gynaecological
Ovarian cyst rupture, twist, bleed
Ectopic pregnancy

38
Q

Causes of diffuse abdo pain

A

Obstruction
Infection: Peritonitis, Gastroenteritis
Inflammation: IBD
Ischaemia: Mesenteric ischaemia

Medical causes
DKA
Addison’s
Hypercalacemia
Porphyria
Lead poisoning
39
Q

…..

A

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40
Q

…….

A

……

41
Q

…….

A

…….

42
Q

Ascites with cells greater than what is consistent with SBP

A

> 250 cells/mm3

43
Q

3 causes of abdo distension

A
  1. Fluid (ascites- shifting dullness + signs of chronic liver disease)
  2. Flatus (obstruction)
  3. Fat, faeces, fetus
44
Q

Signs of obstruction

A
Nausea, vomiting
Not opened bowel
High-pitched tinkling BS
?Previous surgery (adhesions)
?Tender irreducible femoral hernia in the groin
45
Q

Types of ascites

A

Transudate

Exudate

46
Q

Types of transudate ascites

A

Cirrhosis
Cardiac failure
Nephrotic syndrome

47
Q

Types of exudate ascites

A

Remember this is calculated using SAAG

Malignancy (abdominal, pelvic, peritoneal mesothelioma)

Infection: e.g. TB, pyogenic

EXCEPTIONS (these are due to low serum albumin rather than high ascites alubimin)

Budd–Chiari syndrome (hepatic vein thrombosis), portal vein thrombosis

48
Q

Classify jaundice with causes of each

A

Pre-hepatic
-Haemolysis, defective conjugation

Hepatic
-Hepatitis

Post hepatic
-CBD Obstruction

49
Q

…….

A

…….

50
Q

……..

A

……..

51
Q

Investigation to do for bloody diarroeah?

A

MSC of the stools to look for the bacteria below

52
Q

Blood diarroea causes

A

Infective colitis
Inflammatory colitis
Ischaemic colitis
Diverticulitis, Malignancy

53
Q

Bacteria causing infective colitis

A
Campylobacter
Haemorrhagic E coli
Entamoeba histolytica
Salmonella
Shigella
54
Q

Who is inflammatoy colitis (IBD) common in, and who is it more common in

A

Young, Extra-GI manifestations

55
Q

Who is ischaemic colitis present in

A

Elderly

56
Q

Obsructed bowel what blood markers could be high

A

Lactate and CK

57
Q

Management of acute GI bleeds

What if you find it is a variceal bleed

When do you give antibiotics

A
ABC
IV access
Fluids
G&amp;S, X-match blood
OGD

Variceal bleed

  • Antibiotics
  • Terlipressin
58
Q

Investigations for acute abdomen

A

FBC, U&Es, LFTs, CRP, Clotting, G&S, X-match
Erect CXR
CT

59
Q

Management of acute abdomen

A
NBM
Fluids
Analgesic
Anti-emetics
Antibiotics
Monitor vitals &amp; UO
60
Q

Investigation for jaundice

A

Bloods: FBC, LFTs, CRP

Abdominal USS
after a fast (gallstones better visualized in a distended, bile-filled gallbladder)

61
Q

Investigations for dysphagia and weight loss

A

OGD & Biopsy

62
Q

Investigations for PR bleed and wt loss

A

Colonoscopy

63
Q

Management of ascites

A

Diuretics (spironolactone ± furosemide)

Dietary sodium restriction

Fluid restriction in patients with hyponatraemia

Monitor wt daily

Therapeutic paracentesis (with IV human albumin)

64
Q

What calculation should you do for ascites and what can it tell you

A

The gradient
Serum albumin-ascites albumin:

> 11g/L:
Cirrhosis, Cardiac failure

<11 g/L:
TB, Cancer, (Nephrotic syndrome)

65
Q

Why will the gradient between serum albumin and ascites albumin be low in nephrotic syndrome

A

Becuse the serum albulin is low because you leak proteins into the urine

66
Q

How do you manage encephalopathy

A

Lactulose
Phosphate enemas

Avoid sedation
Treat infections
Exclude a GI bleed

67
Q

Why would you want to exclude a GI bleed in encephalopathy

A

Because someone with chronic liver disease is prone to a GI bleed, and the blood will act as a substate for bacteria in the GI tract to metabolise and produce toxins from

68
Q

Why do you give lactulose in encephalopathy

A

To reduce transit time so that there is less time for bacteria to make toxins

69
Q

Post-op care complications in abdo surgery

A

Wound infection

Anastomotic leak

Pelvic abscess
e.g. post-appendectomy

70
Q

What are the featres of wound infection

A

Erythematosus

Discharge

71
Q

What are the features of an anastomotic leak

A

Diffuse abdo tenderness
Guarding, rigidity
Hypotensive/tachycardic

72
Q

What are the features of pelvic abscess (e.g. post-appendectomy)

A

Pain, fever, sweats, mucus diarrhoea

73
Q

Presentation and treatment of a perianal abscess

A

Tender, red swelling

Incision & drainage

74
Q

Presentation and treatment of an anal fissure

A

Rectal pain (defaecation)
Stool coated with blood
Advice re diet (fluids, fibre)
GTN cream

75
Q

Presentation of IBS

A

Recurrent abdo pain, bloating
Improves with defecation
Change in the frequency/form of stool

76
Q

What red flags might be seen with IBS

A

No PR bleed, anaemia, wt loss or nocturnal symptoms, exclude Coeliac

77
Q

A good question to ask somebody you suspect to have IBS/IBD

A

Is there nocturnal symptoms

IBD have them IBS don’t

78
Q

Treatment for IBS

A

Diet & Lifestyle modification

Symptomatic treatment:

  • Abdo pain: antispasmodics
  • Laxatives for constipation
  • Anti-diarrhoeals
79
Q

Respiratory assocaited symptoms to ask about?

A

WBC:

Wheeze, breathlessness, cough (then leads you onto… ) sputum, haemoptysis, weight loss

Chest pain

80
Q

What is ciclosporine main side effect

A

Use as immunosuppresant following renal trasplant

Cause gum hypertrophy

81
Q

Retrosternal pain with high alcohol consumption

A

Gastritis