Case 4 CVD Flashcards

1
Q

Define CVD

A

Cardiovascular disease (CVD) is a general term that describes a disease of the heart or blood vessels.

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2
Q

How can blood flow to the heart, brain or body be reduced?

A
  • blood clot (thrombosis)
  • build-up of fatty deposits inside an artery, leading to the artery hardening and narrowing (atherosclerosis)
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3
Q

What are the types of CVDs?

A
  • coronary heart disease
  • heart failure,
  • rheumatic fever/rheumatic heart disease
  • stroke
  • congenital heart disease.
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4
Q

What are the risk factors for CVDs?

A
  • Hypertension
  • Cigarette smoking & second hand smoking.
  • Elevated cholesterol
  • Diabetes
  • Obesity/overweight
  • Physical inactivity
  • Family history and genomic
  • Glucose levels

Prevalence of key risk factors, varies greatly according to geographical region, gender, and ethnic background

risk factors enhance each others influence.

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5
Q

Why is hypertension a risk factor for CVDs?

A
  • High BP can damage arteries by making them less elastic = decreases flow of blood & oxygen to heart & leads to heart disease
  • When high BP for many years = relative risk increases by 2
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6
Q

Why is elevated cholesterol a risk factor for CVD?

A
  • Dyslipidaemia - Increased levels of total & low density lipoprotein (LDL)-cholesterol.
  • High-density lipoprotein (HDL cholesterol): Protects you from CVD
  • When HDL decrease = increased risk in CVD.
    Lower HDL & higher total cholesterol = higher risk of CVD
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7
Q

Why is obesity a risk factor for CVD?

A
  • High waist circumference (obese) = doubling of risk
  • Can cause increase in LDL & decrease HDL
  • BP rise
  • Can lead to diabetes
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8
Q

Why are glucose levels a risk factor for CVD?

A
  • When have diabetes = increased risk.
  • Over time, high blood sugar can damage blood vessels & nerves that control your heart
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9
Q

What is primary prevention for CVD?

A
  • timely identification of people at increased risk
  • ABCDE approach
  • Cigratee smoking prevention & intervention
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10
Q

What is primary prevention aimed at for CVD?

A

prevention of the risk factors for CVD

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11
Q

What is the ABCDE approach?

A
  • aspirin/antiplatelet therapy (A)
  • blood pressure & hypertension (B)
  • Cholesterol & dyslipidemia (C)
  • diet & nutrititon - lifestyle (D)
  • exercise & physical activity (E)
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12
Q

What are the benefits of regular physical activity?

A
  • Healthy blood pressure
  • healthy weight
  • healthy lipid levels
  • low levels of inflmation
  • insulin sensitivity
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13
Q

How much physical activity is recomended per week according to the ACBDE approach?

A

150 minutes per week of moderate intensity physical activity in at least 3–4 sessions per week each lasting approximately 40 minutes, for LDL-C and blood pressure reduction.

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14
Q

What is an example of primary prevention of CVDs using the ABCDE approach?

A

A pedometer can be an effective tool for intervention with one guideline, for example, recommending walking at least 10,000 steps a day.

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15
Q

Explain the cigarette smoking prevention & intervention for CVDs

A

5A’s of smoking cessation counselling:
* ‘Ask’ (assess tobacco use at every visit)
* ‘Advise’ (strongly urge quitting)
* ‘Attempt’ (try to identify smokers ready to quit)
* ‘Assist’ (aid the patient in quitting)
* ‘Arrange’ (for follow-up contacts)

  • Interventions for smoking are varied & vary per group (youth/adults)
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16
Q

What can be done for secondary prevention of CVDs?

A
17
Q

What does secondary prevention focus on?

A

those who already have manifestations of disease, but where aggressive control of risk factors can have a major impact in preventing recurrences of disease.

18
Q

What does secondary prevention focus on?

A

those who already have manifestations of disease, but where aggressive control of risk factors can have a major impact in preventing recurrences of disease.

19
Q

What are the prediction models for CVD?

A
  • Framingham risk score
  • SCORE
  • Qrisk
20
Q

What is a limitation of the 3 risk prediction models for CVD?

A

Don’t provide reliable fatal CVD & CHD risk estimates in type 2 diabetes

21
Q

Explain the framingham risk score

A
  • based on age, sex, BP, cholesterol (total & HDL) & smoking,
  • Caucasians
  • Various versions
  • In Europe don’t use this because it takes into account afro-americans and have less afro-americans, so have to use a score that is comparable with the population. But US uses.
22
Q

Explain SCORE

A
  • Systematic Coronary Risk Evaluation (SCORE) Project risk scores for fatal CHD and CVD appear to overestimate risk in the general population and have not been evaluated in diabetes.
  • Used in EUrope, CVD risk in countries with high and low risk, e.g. NL is low risk.
23
Q

Explain Qrisk

A
  • Following recognition of glycemia as a CVD risk factor, the Diabetes Epidemiology: Collaborative Analysis of Diagnostic Criteria in Europe (DECODE) Study Group developed a fatal CVD risk equation incorporating glucose tolerance status and fasting plasma glucose
  • high CVD risk in England, Wales.